rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    non sort: The
    title: quinolones
  name:
    name part: Andriole, Vincent T.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: enk
    place:
      place term: London
    place:
      place term: San Diego
    publisher: Academic Press
    date issued: 1988
    issuance: monographic
  language:
    language term: eng
  physical description:
    reformatting quality: access
    form: remote
    extent: 1 online resource (xii, 262 pages) : illustrations
  abstract: The Quinolones covers reviews on the history, chemistry and mechanism of action, in vitro properties, pharmacokinetics, clinical overview, toxicity, adverse effects and drug interactions, and future prospects of the 4-quinolones. The book discusses the microbiology of quinolones, particularly with consideration of the development of resistance, pharmacology, toxicology, and clinical uses. Chemists, microbiologists, pharmacologists and clinicians will find the book useful.
  table of contents: Front Cover; The Quinolones; Copyright Page; Contributers; Preface; Table of Contents; Chapter 1. The Quinolones: History and Overview; 1.1 Mechanism of action; 1.2 Activity in vitro; 1.3 Bacterial resistance; 1.4 Clinical pharmacology; 1.5 Clinical uses; 1.6 Adverse effects; 1.7 Summary; References; Chapter 2. Chemistry and Mechanisms of Action of the Quinolone Antibacterials; 2.1 Chemistry; 2.2 Target site; 2.3 Selectivity; 2.4 Antibacterial activities; 2.5 4-Quinolone interactions with ions; 2.6 4-Quinolone interactions with oxygen; 2.7 4-Quinolone interactions with other antibacterials.
  table of contents: 2.8 ResistanceReferences; Chapter 3. In vitro Properties of the Quinolones; 3.1 Gram-negative aerobes; 3.2 Gram-positive aerobes; 3.3 Anaerobes; 3.4 Miscellaneous organisms; 3.5 Development of resistance; 3.6 Conclusion; References; Chapter 4. Pharmacokinetics of Fluorinated Quinolones; Introduction; 4.1 Serum concentrations; 4.2 Urine concentrations; 4.3 Steady state; 4.4 Pharmacokinetics; 4.5 Elimination; 4.6 Bioavailability; 4.7 Impaired renal function; 4.8 Impaired liver function; 4.9 Impact of food; 4.10 Interactions; 4.11 Influence of disease; 4.12 Extravascular penetration; References.
  table of contents: Chapter 5. Clinical Overview of the Newer 4-Quinolone Antibacterial AgentsIntroduction; 5.1 Urinary tract infections; 5.2 Respiratory tract infections; 5.3 Gastrointestinal infections; 5.4 Skin and soft-tissue infections; 5.5 Osteomyelitis; 5.6 Sexually transmitted diseases; 5.7 Immunocomprised patients; 5.8 Central nervous system infections; 5.9 Other potential uses; 5.10 Summary; References; Chapter 6. Safety Overview: Toxicity, Adverse Effects and Drug Interactions; 6.1 Introduction; 6.2 Toxicity of quinolones; 6.3 Adverse effects of fluoroquinolones in clinical studies.
  table of contents: 6.4 Drug interactionsReferences; Chapter 7. The Quinolones: Prospects; 7.1 Microbiology; 7.2 Resistance of bacteria to quinolones; 7.3 Pharmacology; 7.4 Toxicological issues; 7.5 Clinical considerations for future use of quinolones; 7.6 Prophylactic use of quinolones; 7.7 Summary; References; Index.
  note: edited by Vincent T. Andriole.
  note: Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL
  note: digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL
  note: Includes bibliographical references and index.
  note: English.
  subject:
    topic: Quinolone antibacterial agents
  subject:
    topic: Quinolones
  subject:
    topic: Quinolones
  subject:
    topic: MEDICAL
    topic: Pharmacology
  subject:
    topic: Quinolone antibacterial agents
  subject:
    topic: Chimiothérapie
  subject:
    topic: Quinoléines
  subject:
    topic: Gyrasehemmer
  subject:
    topic: Medicine
    topic: Drug therapy
    topic: Quinolones
  classification: RM666.Q55 Q58 1988
  classification: 615/.3
  classification: QV 250 Q68 1988
  classification: VS 8500
  related item:
    title info:
      title: Quinolones
    origin info:
      publisher: London ; San Diego : Academic Press, 1988
    identifier: (DLC) 89175399
    identifier: (OCoLC)19982881
  identifier: 012059515X
  identifier: 9780120595150
  identifier: 9781483216034
  identifier: 1483216039
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: OCLCE
    record creation date: 100324
    record change date: 20260326172720.9
    record identifier: in00005740685
    language of cataloging:
      language term: eng