Tuberculosis : a comprehensive clinical reference /

This book provides all the vital information you need to know about tuberculosis, especially in the face of drug-resistant strains of the disease. Coverage includes which patient populations face an elevated risk of infection, as well as which therapies are appropriate and how to correctly monitor o...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Schaaf, H. Simon, Zumla, Alimuddin, Grange, John M.
Format: eBook
Language:English
Language Notes:English.
Published: [Edinburgh] : Saunders/Elsevier, 2009.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Front Cover; Tuberculosis: A Comprehensive Clinical Reference; Copyright Page; Contents; Foreword; Preface; Contributors; Dedication; Acknowledgements; Abbrevations; Section 1: History and Epidemiology of Tuberculosis; Chapter 1: The history of tuberculosis: Past, present, and challenges for the future; Conquests and Empires; EBB Tide; Discovery of the Cause; Diagnosis; The Search for a Cure; Challenges; Chapter 2: Transmission of Mycobacterium tuberculosis; Introduction and Historical Perspective; Epidemiological Data on the Determinants of Tuberculosis Transmission
  • Mycobacterial Factors, Strain Differences, and Interactions with Source, Environment, and HostHuman Host Factors which Affect Vulnerability to Tuberculosis Infection; Mathematical Modelling of M. Tuberculosis Transmission; Future Prospects and Other Important Considerations in Infection Control; Chapter 3: The global epidemiology of tuberculosis; Natural History of Tuberculosis; Conclusions; References; Chapter 4: Molecular methods and their application in tuberculosis epidemiology; Introduction; Current Genotyping Methods Used in Epidemiological Studies of Tuberculosis
  • The Interpretation of Molecular Epidemiology DataThe Application of Molecular Epidemiology to Tuberculosis; Summary; References; Chapter 5: Epidemiology of childhood tuberculosis; Introduction; Definitions; Transition Framework; Sources of Information; Global Estimates of Burden of Disease in Children; Epidemiology of Transitions; The Way Forward; References; Section 2: Basic Science; Chapter 6: The genus Mycobacterium and the Mycobacterium tuberculosis complex; The Mycobacteria and the Tubercle Bacillus
  • An Historical Introduction; Classification of the Genus Mycobacterium
  • The Ecology of MycobacteriaGrowth Characteristics and Metabolism of Mycobacteria; Antigenic Structure of Mycobacteria; Macromolecular Structure of Mycobacteria; Definition of the M. Tuberculosis Complex; The Genome of M. Tuberculosis and Other Mycobacteria; Culture; Treatment; Mycobacteriophages, Lysogeny, and Phage Typing; Plasmids or Episomes; The Evolution and Devolution of the M. Tuberculosis Complex; Determinants of Virulence and Pathogenicity; Chapter 7: Other mycobacteria causing human disease; Introduction; Epidemiology and Risk Factors; Bacteriology
  • Migrants and Tuberculosis Disease in High-Burden CountriesTransmission and Pathogenesis; Clinical Presentation and Diagnosis; Prevention of NTM Infections; References; References; Chapter 8: The basic immunology of tuberculosis; Introduction; Protective Immunity; Dendritic Cells; The Role of Toll-Like Receptors; Phagosomal Maturation and Antigen Processing; Discussion; Macrophage and Dendritic Cell Cytokine Production; The Activation of T-Lymphocytes; T-Lymphocyte and NK Cell Functions; Interferon-gamma; Chemokines, Adhesion Molecules and Cellular Migration; Microbial Elimination