http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
1 online resource (xvi, 392 pages) : illustrations
This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical scavenging drugs. Oxidative stress may be influenced by exogenous agents of oxidative stress, radiation, trauma, drug activation, oxygen excess, or by exogenous oxidative stress which is associated with many pathological states including chronic inflammatory disorders, cardiovascular disease, injury to the central nervous system, and connective tissue damage. Thi.
Chemistry of iron and copper in radical reactions / W.H. Koppenol -- Some chemical and biochemical constraints of oxidative stress in living cells / Jean Chaudiere -- Ferryl iron and protein free radicals / C.E. Cooper -- Antioxidants and free radical scavengers / A.T. Diplock -- Formation of free radicals and mechanisms of action in normal biochemical processes and pathological states / C.A. Rice-Evans -- Free radicals and cell proliferation / R.H. Burdon -- Therapeutic iron-chelating agents / S. Singh and R.C. Hider -- Free radicals in central nervous system injury / E.D. Hall -- Ultraviolet radiation (UVA, UVB) and skin antioxidants / L. Packer -- Free radicals and atherosclerosis / J.C. Fruchart and P. Duriez -- Chemical aspects of free radical reactions in connective tissue / B.J. Parsons -- Free radicals and connective tissue damage / M.S. Baker -- Free radicals in toxicology with an emphasis on electron spin resonance investigations / R.P. Mason and C.F. Chignell -- Radical generation and detection in myocardial injury / B. Kalyanaraman [and others] -- Free radical pathways in the inflammatory response / P.G. Winyard [and others].
editors, Catherine A. Rice-Evans, Roy H. Burdon.
Includes bibliographical references and index.