Autophagy in mammalian systems. Part B /

Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal "house-cleaning" in the cell is called autophagy - literally self-eating. Breakthroughs in unde...

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Bibliographic Details
Corporate Author:	ScienceDirect (Online service)
Other Authors:	Klionsky, Daniel J. (Editor)
Format:	eBook
Language:	English
Published:	San Diego, California ; London : Academic Press/Elsevier, ©2009.
Series:	Methods in enzymology ; volume 452.
Subjects:	Cellular control mechanisms. Autophagic vacuoles. Apoptosis. Eukaryotic cells. Biological assay. Autophagy > physiology Cells > metabolism Apoptosis Eukaryotic Cells Mammals > metabolism Microtubule-Associated Proteins > metabolism Biological Assay Régulation cellulaire. Apoptose. Cellules eucaryotes. Essais biologiques. SCIENCE > Life Sciences > Biochemistry. Biological assay Autophagic vacuoles Cellular control mechanisms Eukaryotic cells degradatie degradation katabolisme catabolism celfysiologie cell physiology Metabolic Processes Metabole processen Electronic books.
Online Access:	Connect to the full text of this electronic book

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Summary:	Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal "house-cleaning" in the cell is called autophagy - literally self-eating. Breakthroughs in understanding the molecular basis of autophagy came after the cloning of ATG1 in yeast. These ATG genes in yeast were the stepping stones to the explosion of research into the molecular analysis of autophagy in higher eukaryotes. In the future, this research will help to design clinical approaches that can turn on autophagy and halt tumor growth. In this volume, a robust slate of methods for conducting research are presented, establishing a consensus of appropriate criteria for monitoring autophagy. Along with Autophagy: Lower Eukaryotes, this volume marks the seminal collection of methods in the burgeoning field of autophagy
Item Description:	Called Part B in continuation of Part A issued as volume 451 of Methods in enzymology under title: Autophagy : Lower eukaryotes and non-mammalian species, Part A.
Physical Description:	1 online resource (xlix, 508 pages, 12 unnumbered pages of plates) : illustrations (some color)
Bibliography:	Includes bibliographical references and indexes.
ISBN:	9780080923253 0080923259 9780123745477 0123745470
ISSN:	0076-6879 ;