The molecular basis of cancer /
Successfully fighting cancer starts with understanding how it begins. This thoroughly revised 3rd Edition explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of cancer. A team of leading experts thoroughly explain the molecular b...
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| Format: | eBook |
| Language: | English |
| Language Notes: | English. |
| Published: |
Philadelphia, PA :
Saunders/Elsevier,
©2008.
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| Edition: | 3rd ed. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Cancer: a genetic disorder
- Oncogenes and signal transduction
- Tumor suppressor genes
- DNA repair pathways and human cancer
- Epigenetics and cancer
- Infectious agents and cancer
- Environmental carcinogenesis
- Animal models: flies, fish, and yeast
- Genetic mosue models of cancer
- Cancer stem cells
- Signal transduction by growth factor receptors
- Cell growth
- Regulation of the cell cycle
- Metabolism of cell growth and proliferation
- Apoptosis, autophagy, and necrosis
- Cellular senescence
- The tumor microenvironment in cancer progression
- Tumor angiogenesis
- Invasion and metastasis
- Cancer genomics
- Transcriptome analysis
- Mass spectrometry in cancer biology
- Imaging and cancer
- Bioinformatics
- Early detection of cancer: molecular screening
- Lymphoma/myeloma
- Molecular genetics of ALL
- Biology of chronic and acute myeloid leukemia
- Molecular biology of childhood neoplasms
- Molecular basis of lung cancer
- Molecular abnormalities in colon and rectal cancer
- Breast cancer
- Molecular basis of prostate cancer
- Molecular pathogenesis of epithelial ovarian cancer
- Molecular pathogenesis of pancreatic adenocarcinoma
- Molecular biology of melanoma
- Soft-tissue sarcomas
- Head and neck squamous cell carcinoma
- Primary brain tumors
- Epithelial skin cancer
- Endocrine cancer
- Gastric and gastroesophageal adenocarcinoma
- From bench to bedside with targeted therapies
- Screening strategies for targeted therapeutics
- Animal models to predict anticancer efficacy
- Pharmacokinetics, pharmacodynamics, and pharmacogenetics
- Phase 1 trials today
- Cancer therapeutics
- Natural and acquired resistance to cancer therapies
- Molecular basis of radiation therapy
- Hematopoietic growth factors and cytokines
- Interferons
- Cancer and the cellular immune response
- Cancer-specific vaccines
- Monoclonal antibody therapy of cancer
- Gene therapy and oncolytic viruses
- RNA as a therapeutic molecule
- Heat shock protein 90 and the proteasome
- Cancer chemoprevention.