rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Genetic diseases of the kidney
  name:
    name part: Lifton, Richard P.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: ne
    place:
      place term: Amsterdam
    place:
      place term: Boston
    publisher: Elsevier/Academic Press
    date issued: 2009
    edition: 1st ed.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xiv, 829 pages, 50 unnumbered pages of plates) : illustrations (some color)
  abstract: Genetic Diseases of the Kidney identifies and analyzes genetic abnormalities causing renal diseases in human subjects. Although in a sense the genome contains all the instructions required for the formation of a phenotype, the information is encoded in an extremely complicated fashion. In primary genetic diseases, the genetic instruction specifies a phenotype clearly linked with a discreet lesion confined to the kidney. However, the genetic disturbance may be imbedded in a complicated physiologic ensemble, so that the nexus between the genetic disturbance and the phenotype may be obscured; in consequence, the causal sequence is extremely difficult to unravel. In many instances the renal disease is one component of a complicated systemic hereditary disease, either monogenic or polygenic. Indeed, renal disease may arise as the sum of minor inputs from many different, seemingly unrelated genes, so that the genetic contributions may be difficult to identify. Confounding the problem further are environmental influences, originating either in the chromosomal environment from modifier genes, or in the extra-chromosomal environmental from intrauterine or postnatal influences. These considerations have determined both the organization of the text as well as the detailed description of the genetic disorders and the physiologic derangements that emerge. * Lays the essential foundation of mammalian genetics principles for medical professionals with little to no background in genetics. Analyzes specific renal diseases - both monogenic disorders confined to the kidney as well as systemic diseases with renal involvement - and explains their genetic causes. World-renowned editors and authors offer expert frameworks for understanding the links between genes and complex clinical disorders (i.e., lupus, diabetes, HIV, and hypertension).
  table of contents: pt. 1. General background -- pt. 2 -- pt. 3. Genetic abnormalities of renal development and morphogenesis -- pt. 4. Inherited neoplastic diseases affecting the kidney -- pt. 5. Systemic diseases with renal involvement : monogenic disorders -- pt. 6. Systemic hereditary diseases with renal involvement : multifactorial diseases.
  note: edited by Richard P. Lifton [and others].
  note: Includes bibliographical references and index.
  note: English.
  subject:
    topic: Kidneys
    topic: Diseases
    topic: Genetic aspects
  subject:
    topic: Kidney Diseases
    topic: genetics
  subject:
    topic: Kidney Diseases
    topic: physiopathology
  subject:
    topic: Reins
    topic: Maladies
    topic: Aspect génétique
  subject:
    topic: MEDICAL
    topic: Nephrology
  subject:
    topic: Kidneys
    topic: Diseases
    topic: Genetic aspects
  classification: RC903 .G46 2009
  classification: 616.61042
  classification: 2009 B-993
  classification: WJ 300 G3277 2009
  related item:
    title info:
      title: Genetic diseases of the kidney
    origin info:
      publisher: Amsterdam ; Boston : Elsevier/Academic Press, 2009
      edition: 1st ed.
    identifier: (OCoLC)253210872
  identifier: 9780124498518
  identifier: 0124498515
  identifier: 9780080924274
  identifier: 0080924271
  identifier: 1282168916
  identifier: 9781282168916
  identifier: 9786612168918
  identifier: 6612168919
  identifier: 97502:97505 Elsevier Science & Technology
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: OPELS
    record creation date: 090413
    record change date: 20260326161929.1
    record identifier: in00005737556
    language of cataloging:
      language term: eng