Programmed cell death. Part A, General principles for studying cell death /

The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E. Sulston (UK) "for their discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental aspect of embryon...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Khosravi-Far, Roya (Editor), Zakeri, Zahra, 1952- (Editor), Lockshin, R. A. (Richard A.) (Editor), Piacentini, Mauro (Editor)
Format: eBook
Language:English
Language Notes:English.
Published: San Diego, California : Academic Press/Elsevier, ©2008.
Series:Methods in enzymology ; v. 442.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E. Sulston (UK) "for their discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental aspect of embryonic development, normal cellular turnover and maintenance of homeostasis (maintaining a stable, constant environment) on the one hand, and aging and disease on the other. This volume addresses the significant advances with the techniques that are being used to analyze cell death. * This volume provides the necessary, trusted methods to carry out this research on the latest techniques. Once researchers understand the molecular mechanisms of the apoptotic pathways, they can begin to develop new therapies. * Presents key methods on studying tumors and how these cancer cells evade cell death. * Eliminates searching through many different sources to avoid pitfalls so the same mistakes are not made over and over.
Physical Description:1 online resource (xlviii, 493 pages, 15 unnumbered pages of plates) : illustrations (some color)
Bibliography:Includes bibliographical references and index.
ISBN:9780080921648
0080921647
0123743125
9780123743121
ISSN:0076-6879 ;