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Handbook of process chromatography : development, manufacturing, validation and economics.

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This book will update the original edition published in 1997. Since the publication of the first edition, the biotechnology and biologics industries have gained extensive knowledge and experience in downstream processing using chromatography and other technologies associated with recovery and purifi...

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Bibliographic Details
Main Author: Hagel, Lars
Corporate Author: ScienceDirect (Online service)
Other Authors: Jagschies, Günter, Sofer, G. K.
Format: eBook
Language:English
Published: London ; Burlington, MA : Academic, 2008.
Edition:2nd ed. /
Subjects:
Chromatographic analysis > Industrial applications.
Chromatographie > Applications industrielles.
Chromatographic analysis > Industrial applications
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Preface
  • Acknowledgements
  • 1. Biopharmaceuticals Today
  • 2. Process Capability and Production Scenarios
  • 3. Process Design Concepts
  • 4. Separation Technologies
  • 5. Analysis
  • 6. Cleaning and Sanitization
  • 7. Validation
  • 8. Economics
  • 9. Basic Properties of Peptides, Proteons, Nucleic Acids, and Virus Particles
  • 10. Optimization of Chromatographic Separations
  • 11. Equipment
  • 12. Column Packing
  • Appendix A. Symbols and Definitions in Liquid Chromatography
  • Appendix B. Dimensionless Numbers
  • Appendix C. Activities for Biopharmaceutical Production from Genetically Engineered Mammalian Cells
  • Appendix D. Simulations Using the Supplied Software.