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Principles of nucleic acid structure /

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This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially impo...

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Bibliographic Details
Main Author: Neidle, Stephen
Corporate Author: ScienceDirect (Online service)
Format: eBook
Language:English
Language Notes:English.
Published: Amsterdam : Boston : Elsevier ; Academic Press, 2008.
Edition:1st ed.
Subjects:
Nucleic acids.
Nucleic Acid Conformation
Nucleic Acids
Nucleic Acids > chemistry
Acides nucléiques.
Acides nucléiques > Conformation.
SCIENCE > Chemistry > Organic.
Nucleic acids
Molekulargenetik
Electronic books.
dissertations.
Academic theses
Academic theses.
Thèses et écrits académiques.
Online Access:Connect to the full text of this electronic book
Description
Summary:This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, the book includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. In particular, the reader will find extensive new discussions on: RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA). This handy guide ends with a complete list of resources, including relevant online databases and software. * Completely updated with expanded discussion of topics such as RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA) * Includes a complete list of resources, including relevant online databases and software * Defines technical lingo for novices.
Physical Description:1 online resource (xii, 289 pages) : illustrations
Format:Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Bibliography:Includes bibliographical references and index.
ISBN:9780080553528
0080553524