The chemistry and pharmacology of Taxol and its derivatives /

Taxol®, a naturally occurring diterpenoid is one of the most exciting antitumor drugs available today. Its current indications (refractory ovarian and metastatic breast cancer) may soon be expanded since the drug is showing activity against lung and head-and-neck cancers. The book opens with a revie...

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Bibliographic Details
Corporate Author:	ScienceDirect (Online service)
Other Authors:	Farina, Vittorio
Format:	eBook
Language:	English
Published:	Amsterdam ; New York : Elsevier, 1995.
Series:	Pharmacochemistry library ; v. 22.
Subjects:	Paclitaxel. Paclitaxel > Derivatives. Paclitaxel > chemistry Paclitaxel > pharmacology Paclitaxel Paclitaxel > analogs & derivatives Paclitaxel > Dérivés. MEDICAL > Pharmacology. Paclitaxel > Derivatives Taxoïden. Farmacologia. Quimica farmaceutica. Drogas. Drugs Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

Naturally occurring taxoids ; The structural elucidation of taxoids / G. Appendino
Paclitaxel (Taxol®) formulation and prodrug / D. Vyas
Metabolism and pharmacology of taxoids / M. Wright [and others]
Paclitaxel (Taxol®) chemistry and structure activity relationships / S.H. Chen, V. Farina
The chemistry of the Taxol® side chain : synthesis, modifications and conformational studies / J. Kant
The biochemical pharmacology of Taxol® and mechanisms of resistance / T. MacDonald, L. Landino.