XIVth International Symposium on Medicinal Chemistry : Maastricht, 8-12 September 1996 /

Vaso-occlusive disorders including unstable angina, myocardial infarction, transient ischemic attacks, stroke and peripheral artery disease remain the major sources of morbidity and mortality in western civilization. Platelet activation and resulting platelet aggregation play a major role in the pat...

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Bibliographic Details
Corporate Authors: International Symposium on Medicinal Chemistry Maastricht, Netherlands, ScienceDirect (Online service)
Other Authors: Awouters, Frans, 1937-
Format: Conference Proceeding eBook
Language:English
Published: Amsterdam ; New York : Elsevier, 1997.
Series:Pharmacochemistry library ; v. 28.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:Vaso-occlusive disorders including unstable angina, myocardial infarction, transient ischemic attacks, stroke and peripheral artery disease remain the major sources of morbidity and mortality in western civilization. Platelet activation and resulting platelet aggregation play a major role in the pathogenesis of these thromboembolic diseases. Recognition of the contribution of platelets to the pathophysiology of cardiovascular disease has provided impetus for the continued search for new antiplatelet agents. Hence, over the past two decades many strategies have been evaluated in the search for efficacious mechanisms to reduce platelet function. The medical need for more efficacious antithrombotic drugs and the growing understanding of the role of platelets in vascular injury have catalyzed the extensive evaluation of novel approaches to control platelet function. Along these lines, the volume therefore provides an in-depth assessment of ongoing clinical trials, new and clinically established agents, and other developments in this rapidly developing field.
Physical Description:1 online resource (xiii, 561 pages) : illustrations
Bibliography:Includes bibliographical references and indexes.
ISBN:9780444827982
0444827986
9780080543888
008054388X