http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
1 online resource (xvi, 323 pages, 2 unnumbered pages of plates) : illustrations (some color)
The first of its kind, this volume presents the latest research findings on the chaperonins, the best studied family of a class of proteins known as molecular chaperones. These findings are changing our view of some fundamental cellular processes involving proteins, especially how proteins fold into their functional conformations. Key Features * Origins of the new view of protein folding * Prokaryotic chaperonins * Eukaryotic chaperonins * Evolution of the chaperonins * Refolding of denatured proteins * Organelle biosynthesis * Biomedical aspects.
R.J. Ellis, Chaperonins: Introductory Perspective. R.S. Gupta, Evolutionary Relationships of Chaperonins. A.A. Gatenby, Chaperonins of Photosynthetic Organisms. T. Langer and W. Neupert, Chaperonin-Mediated Folding and Assembly of Proteins in Mitochondria. K.R. Willison and A.L. Horwich, Structure and Function of Chaperonins in Archaebacteria and Eukaryotic Cytosol. S.M. Van Der Veis and C. Georgopoulos, Regulation of Chaperonin Gene Expression. A.R. Clarke and P.A. Lund, Kinetic and Energetic Aspects of Chaperonin Function. J. Martin, M. Mayhew and F. Ulrich-Hartl, Role of Prokaryotic Chaperonins in Protein Folding. H.R. Saibil, Chaperonin Structure and Conformational Changes. A.R.M. Coates, Immunological Aspects of Chaperonins. Subject Index.
Chaperonins : introductory perspective / R. John Ellis -- Evolutionary relationships of chaperonins / Radhey S. Gupta -- Chaperonins of photosynthetic organisms / Anthony A. Gatenby -- Chaperonin-mediated folding and assembly of proteins in mitochondria / Thomas Langer and Walter Neupert -- Structure and function of chaperonins in archaebacteria and eukaryotic cytosol / Keith R. Willison and Arthur L. Horwich -- Regulation of chaperonin gene expression / Saskia M. van der Vies and Costa Georgopoulos -- Kinetic and energetic aspects of chaperonin function / Anthony R. Clarke and Peter A. Lund -- Role of prokaryotic chaperonins in protein folding / Jörg Martin, Mark Mayhew, and F.-Ulrich Hartl -- Chaperonin structure and conformational changes / Helen R. Saibil -- Immunological aspects of chaperonins / Anthony R.M. Coates.
Includes bibliographical references and index.
81041:81041 Elsevier Science & Technology