rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Molecular biology of B cells
  name:
    name part: Honjo, T. (Tasuku)
    name part: 1942-
  name:
    name part: Alt, Frederick W.
  name:
    name part: Neuberger, M. S. (Michael S.)
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  genre: Internet Resources.
  genre: Illustrations.
  origin info:
    place:
      place term: ne
    place:
      place term: Amsterdam
    place:
      place term: Boston
    publisher: Elsevier
    date issued: 2004
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xiv, 589 pages) : color illustrations
  abstract: Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists.
  table of contents: ORGANIZATION, REARRANGEMENT AND TRANSCRIPTION OF IMMUNOGLOBULIN GENES -- Human Immunoglobulin heavy chains locus -- Immunoglobulin heavy chain genes of mouse -- Immunoglobulin? genes of human and mouse -- Immunoglobulin lambdav (IGL) genes of human and mouse -- The Mechanism of V(D) J Recombination -- Transcription of Immunoglobulin genes -- B CELLS AND THEIR DEVELOPMENT -- Early B cell development to a mature, antigen-sensitive cell -- cellular stages and molecular decisions -- Allelic exclusion, Isotypic exclusion and the Developmental Regulation of V(D)J Recombination -- The Development of Human B Lymphocytes -- Development and function of B cell subsets -- B CELL DIFFERENTIATION INDUCED BY Ag STIMULATION -- Structure and function of B cells antigen receptor complexes -- Regulation of antigen receptor signaling by the co-receptors, CD19 and CD22 -- The dynamic structure of antibody responses -- Dynamics of B cell migration to and within secondary lymphoid organs -- Characteristics of mucosal B cells with emphasis on the human secretory immune system -- The Cellular Basis of B Cell Memory -- Immunoglobulin assembly and secretion -- Fc And Complement Receptors -- Ig GENE ALTERATION IN PERIPHERY -- Regulation of Class Switch Recombination -- Molecular Mechanism of Class Switch Recombination -- Molecular Mechanism of Hypermutation -- Selection During Antigen-Driven B Cell Immune Responses: The Basis for High Affinity Antibody -- DISEASES OF B CELLS -- Chromosomal Translocations in B-cell Leukemias and Lymphomas -- Classification and Characteristics of Mouse B Cell-Lineage Lymphomas -- B cells producing pathogenic autoantibodies -- Immunodeficiencies Caused by B Cell Defects -- EVOLUTION OF Ig GENES -- Diverse forms of Immunoglobulin Genes in Lower Vertebrates -- Immunoglobulin Genes and Generation of Antibody Repertoires in Higher Vertebrates: A Key Role for GALT -- The zebrafish immune system -- The Origin of V(D)J Diversification -- FUNCTION AND APPLICATION OF IMMU…
  note: edited by Tasuku Honjo, Frederick W. Alt, Michael S. Neuberger.
  note: Includes bibliographical references and index.
  subject:
    topic: Molecular immunology
  subject:
    topic: B cells
  subject:
    topic: Immunoglobulins
  subject:
    topic: Immunoglobulin genes
  subject:
    topic: B-Lymphocytes
    topic: immunology
  subject:
    topic: B-Lymphocytes
  subject:
    topic: Genes, Immunoglobulin
  subject:
    topic: Genetic Phenomena
  subject:
    topic: Immunologie moléculaire
  subject:
    topic: Lymphocytes B
  subject:
    topic: Immunoglobulines
  subject:
    topic: Gènes de l'immunoglobuline
  subject:
    topic: B cells
  subject:
    topic: Immunoglobulin genes
  subject:
    topic: Immunoglobulins
  subject:
    topic: Molecular immunology
  subject:
    topic: B-Lymphozyt
  subject:
    topic: Molekularbiologie
  subject:
    topic: Linfócitos b
  subject:
    topic: Imunologia celular
  subject:
    topic: Imunoglobulinas
  subject:
    topic: Biologia molecular
  classification: QR185.6 .M653 2004eb
  classification: 616.07/98
  classification: 2004 B-470
  classification: WH 200 M7182 2004
  classification: WF 9880
  related item:
    title info:
      title: Molecular biology of B cells
    origin info:
      publisher: Amsterdam ; Boston : Elsevier, 2004
    identifier: (DLC) 2003064380
    identifier: (OCoLC)53970703
  identifier: 9780120536412
  identifier: 0120536412
  identifier: 9780080479507
  identifier: 0080479502
  identifier: 9780323958967
  identifier: 0323958966
  identifier: 2003064380
  identifier: 97397:97398 Elsevier Science & Technology
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: OPELS
    record creation date: 070806
    record change date: 20260326151232.3
    record identifier: in00005732495
    language of cataloging:
      language term: eng