rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Cellular organelles and the extracellular matrix
  name:
    name part: Bittar, E. Edward.
  name:
    name part: Bittar, Neville.
  name:
    name part: ScienceDirect (Online service)
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: ctu
    place:
      place term: Greenwich, Conn
    publisher: JAI Press
    date issued: ©1995
    date issued: 1995
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xii, 292 pages) : illustrations
  abstract: This volume is in two parts. The first contains the remaining chapters on cellular organelles and several chapters relating to organelle disorders. An account of mitochondriopathis is given in the chapter on the mitochondrion rather than in a separate one. The subject matter of this part of the volume shows quite clearly that the interdisciplinary approach to the study of organelles has shed considerable light on the nature of the mechanisms underlying the etiology and pathobiology of many of these disorders. As an example, mutations in the genes encoding integral membrane proteins are found to lead to disturbances in peroxisome assembly. It is also interesting and significant that mistargeting of protein is now thought to be another cause. It will be revealing to see whether mistargeting is the result of mutations in the genes encoding chaperones. The second part of the volume is concerned with the extracellular matrix. It sets out to show that a vast body of new knowledge of the extracellular matrix is available to us. Take for example the integrin family of cell adhesion receptors. It turns out that integrins play a key role not only in adhesion but also in coupling signals to the nucleus via the cytoskeleton. As for fibronectins, they seem to link the matrix with the cytoskeleton by interacting with integrins. Collagen molecules are dealt with in the last two chapters. The boundaries of collagen in disease are defined by drawing a clear line of demarcation between systemic connective tissue disorders (e.g., scleroderma), better known as autoimmune diseases, and the heritable, and the heritable diseases such as osteogenesis imperfect and the Marfan syndrome. This classification takes into account a second group of acquired disorders of collagen forming tissues in which regional fibrosis is the hallmark. Liver cirrhosis and pulmonary fibrosis are prime examples. The decision to place Volumes 2 and 3 before those dealing with cell chemistry was not easily made. It …
  note: edited by E. Edward Bittar, Neville Bittar.
  note: Includes bibliographical references and index.
  subject:
    topic: Cell organelles
  subject:
    topic: Lysosomal storage diseases
  subject:
    topic: Peroxisomal disorders
  subject:
    topic: Extracellular matrix
  subject:
    topic: Lysosomal Storage Diseases
  subject:
    topic: Organelles
  subject:
    topic: Extracellular Matrix
  subject:
    topic: Maladies lysosomiales congénitales
  subject:
    topic: Pathologie peroxysomale
  subject:
    topic: Substance fondamentale (Histologie)
  subject:
    topic: Organites
  subject:
    topic: SCIENCE
    topic: Life Sciences
    topic: Cell Biology
  subject:
    topic: Cell organelles
  subject:
    topic: Extracellular matrix
  subject:
    topic: Lysosomal storage diseases
  subject:
    topic: Peroxisomal disorders
  subject:
    topic: Cells
    topic: Structure
  subject:
    topic: celbiologie
  subject:
    topic: cellular biology
  subject:
    topic: organellen
  subject:
    topic: organelles
  subject:
    topic: Cellular Biology
  subject:
    topic: Celbiologie
  classification: QH581.2 .C453 1995eb
  classification: 574.87/34
  classification: 1996 A-446
  classification: QH 591
  related item:
    title info:
      title: Cellular organelles and the extracellular matrix
    origin info:
      publisher: Greenwich, Conn. : JAI Press, ©1995
    identifier: (DLC) 95024345
    identifier: (OCoLC)32822226
  related item:
    title info:
      title: Cellular organelles and the extracellular matrix
    origin info:
      publisher: Greenwich, Conn. : JAI Press, ©1995
    identifier: (OCoLC)862709547
  related item:
    title info:
      title: Principles of medical biology ; v. 3
  identifier: 9781559388047
  identifier: 1559388048
  identifier: 9780080531496
  identifier: 0080531490
  identifier: 9781559388009
  identifier: 1559388005
  identifier: 95024345
  identifier: 126751:128349 Elsevier Science & Technology
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: OPELS
    record creation date: 070802
    record change date: 20260326150827.4
    record identifier: in00005732036
    language of cataloging:
      language term: eng