Table of Contents:
  • Contributors.
  • Foreword by C.A. Vacanti.
  • Preface to the Second Edition.
  • Preface to the First Edition.
  • Tissue Engineering in Perspective, E. Bell.
  • Introduction to Tissue Engineering:
  • The History and Scope of Tissue Engineering, J.P. Vavanti and C.A. Vacanti.
  • The Challenge of Imitating Nature, R.M. Nerem.
  • Part I: The Basis of Growth and Differentiation:
  • Organization of Cells into Higher Ordered Structures, C.A. Erickson.
  • Dynamics of Cell-ECM Interactions, M. Martins-Green.
  • Matrix Molecules and Their Ligands, B.R. Olsen.
  • Inductive Phenomena, M. Hebrok and D.A. Melton.
  • Morphogenesis and Tissue Engineering, A.H. Reddi.
  • Cell Determination and Differentiation, L.W. Browder.
  • Part II: In Vitro Control of Tissue Development:
  • Mechanical and Chemical Determinants of Tissue Development, D.E. Inger.
  • Animal Cell Culture, G.H. Sato and D.W. Barnes.
  • Regulation of Cell Behavior by Matricellular Proteins, A.D. Bradshaw and E.H. Sage.
  • Growth Factors, T.F. Deuel and N. Zhang.
  • Tissue Engineering Bioreactors, L.E. Freed and G. Vunjak-Novakovic.
  • Tissue Assembly in Microgravity, B.R. Unsworth and P.I. Lelkes.
  • Part III: In Vivo Synthesis of Tissues and Organs:
  • In Vivo Synthesis of Tissues and Organs, L.V. Yannas.
  • Part IV: Models for Tissue Engineering:
  • Organotypic and Histiotypic Models of Engineered Tissues, E. Bell.
  • Quantitative Aspects of Tissue Engineering: Basic Issues in Kinetics, Transport, and Mechanics, A.J. Grodzinsky, R.D. Kamm, and Douglas A. Lauffenburger.
  • Part V: Biomaterials in Tissue Engineering:
  • Patterning of Cells and Their Environment, S. Takayama, R.C. Chapman, R.S. Kane, and G.M. Whitesides.
  • Cell Interactions with Polymers, W.M. Saltzman.
  • Matrix Effects, J.A. Hubbell.
  • Polymer Scaffold Processing, R.C. Thomson, A.K. Shung, M.J. Yaszemski, and A.G. Mikos.
  • Biodegradable Polymers, J.M. Pachence and J. Kohn.
  • Part VI: Transplantation of Engineered Cells and Tissues:
  • Approaches to Transplanting Engineered Cells and Tissues, J. Hardin-Young, J. Teumer, R.N. Ross, and N.L. Parenteau.
  • Cryopreservation, J.O.M. Karlsson and M. Toner.
  • Immunomodulation, D. Faustman.
  • Immunoisolation, B.A. Zielinski and M.J. Lysaght.
  • Engineering Challenges in Immunoisolation Device Development, E.S. Avgoustiniatos, H. Wu, and C.K. Colton.
  • Part VII: Fetal Tissue Engineering:
  • Fetal Tissue Engineering, D.O. Fauza.
  • Pluripotent Stem Cells, M.J. Shamblott, B.E. Edwards, and J.D. Gearhart.
  • Part VIII: Gene Therapy:
  • Gene-Based Therapeutics, L.G. Fradkin, J.D. Ropp, and J.F. Warner.
  • Part IX: Breast:
  • Breast Reconstruction, K.Y. Lee, C.R. Halberstadt, W.D. Holder, and D.J. Mooney.
  • Part X: Cardiovascular System:
  • Blood Vessels, L. Xue and H.P. Greisler.
  • Small-Diameter Vascular Grafts, S.J. Sullivan and K.G.M. Brockbank.
  • Cardiac Prostheses, J.W. Love.
  • Part XI: Cornea:
  • Cornea, V. Trinkaus-Randall.
  • Part XII: Endocrinology and Metabolism:
  • Bioartificial Pancreas, T.G. Wang and R.P. Lanza.
  • Parathyroid, C. Hasse, A Zielke, T. Bohrer, U. Zimmerman, and M. Rothmund.
  • Part XIII: Gastrointestinal System:
  • Alimentary Tract, G.M. Organ and J.P. Vacanti.
  • Liver, H.O. Jauregui.
  • Hepat Assist Liver Support System, C. Mullon and B.A. Solomon.
  • Lineage Biology and Liver, A.S.L. Xu, T.L. Luntz, J.M. Macdonald, H. Kubota, E. Hsu, R.E. London, and L.M. Reid.
  • Part XIV: Hematopoietic System:
  • Red Blood Cell Substitutes, T.M.S. Chang.
  • Lymphoid Cells, U. Chen.
  • Hematopoietic Stem Cells, A. Kessinger and G. Sharp.
  • Part XV: Kidney and Genitourinary System:
  • Renal Replacement Devices, H.D. Humes.
  • Genitourinary System, B.-S. Kim, D.J. Mooney, and A. Atala.
  • Part XVI: Musculoskeletal System:
  • Structural Tissue Engineering, C.A. Vacanti, L.J. Bonassar, and J.P. Vacanti.
  • Bone Regeneration through Cellular Engineering, S.P. Bruder and A.I. Caplan.
  • Articular Cartilage Injury, J.M. McPherson and R. Tubo.
  • Tendons and Ligaments, F. Goulet, D. Rancourt, R. Cloutier, L. Germain, A.R. Poole, and F.A. Auger.
  • Mechanosensory Mechanisms in Bone, S.C. Cowin and M.L. Moss.
  • Myoblast Therapy, J.C. Cousins, J.E. Morgan, and T.A. Partridge.
  • Part XVII: Nervous System:
  • Protection and Repair of Hearing, R.A. Altschuler, Y. Raphael, J. Schacht, D.J. Anderson, and J.M. Miller.
  • Vision Enhancement Systems, G. Dagnelie, M.S. Humayun, and R.W. Massof.
  • Brain Implants, Lars U. Wahlberg.
  • Nerve Regeneration, E.G. Fine, R.F. Valentini, and P. Aebischer.
  • Transplantation Strategies for Treatment of Spinal Cord Dysfunction and Injury, J. Sagen, M.B. Bunge, and N. Kleitman.
  • Neural Stem Cells, M.P. Vacanti.
  • Part XVIII: Periodontal and Dental Applications:
  • Periodontal Applications, N.A. Miller, M.C. Béné, J.P., P. Ambrosini, and G.C. Faure.
  • Regeneration of Dentin, R.B. Rutherford.
  • Part XIX: Skin:
  • Wound Repair: Basic Biology to Tissue Engineering, R.A.F. Clark and A.J. Singer.
  • Skin, N.L. Parenteau, J. Hardin-Young, and R.N. Ross.
  • Dermal Equivalents, G.K. Naughton.
  • Part XX: Womb:
  • Artificial Womb, C.S. Muratore and J.M. Wilson.
  • Part XXI: Regulatory Issues:
  • Regulatory Considerations, K.B. Hellman, R.R. Solomon, C. Gaffey, C.N. Durfor, and J.G. Bishop.
  • Epilogue.
  • Index.
  • Tissue engineering in perspective
  • Introduction to tissue engineering
  • Basis of growth and differentiation
  • In vitro control of tissue development
  • In vivo synthesis of tissues and organs
  • Models for tissue engineering
  • Biomaterials in tissue engineering
  • Transplantation of engineered cells and tissues
  • Fetal tissue engineering
  • Gene therapy
  • Breast
  • Cardiovascular system
  • Cornea
  • Endocrinology and metabolism
  • Gastrointestinal system
  • Hematopoietic system
  • Kidney and genitourinary system
  • Musculoskeletal system
  • Nervous system
  • Periodontal and dental applications
  • Skin
  • Womb
  • Regulatory issues.