Phosphodiesterase inhibitors /
Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of thes...
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| Other Authors: | , , |
| Format: | eBook |
| Language: | English |
| Published: |
San Diego :
Academic Press,
1996.
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| Series: | Handbook of immunopharmacology. Drugs.
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of these new inhibitors are under test as potential anti-inflammatory drugs. During the past five years, molecular biology has revealed a superfamily of these phosphodiesterase isoenzymes. This book summarizes the present state of knowledge, as well as giving a comprehensive description of the compounds available. It will be invaluable for everyone who wants to choose the most suitable PDE inhibitor for their research or who is dealing with such drugs in a clinical setting. Key Features * Utilizes actual testing and research of new PDE inhibitors * Valuable for researchers and students alike. |
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| Physical Description: | 1 online resource (xvi, 228 pages, 2 unnumbered pages of plates) : illustrations (some color) |
| Format: | Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9780122107207 0122107209 9780080538815 0080538819 1281058971 9781281058973 |