http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Gluthione transferases and gamma-glutamyl transpeptidases
1 online resource (xxxvii, 560 pages, 6 unnumbered pages) : illustrations (some color).
This volume on glutathione transferases and gamma-glutamyl transpeptidases serves to bring together current methods and concepts in an interesting, important and rapidly developing field of cell and systems biology. It focuses on particular aspects of the so-called Phase II of drug detoxication, which has important ramifications for endogenous metabolism and nutrition. This volume of Methods in Enzymology presents current knowledge and in this field of research. Together with the volumes on Quinones and Quinone Enzymes (volumes 378 and 382), and on Phase II Conjugation Enzymes and Transport Systems (volume 400), the state of knowledge on proteomics and metabolomics of many pathways of (waste) product elimination, enzyme protein induction and gene regulation and feedback control is provided. We trust that this volume will help stimulate future investigations and speed the advance of knowledge in systems biology. *A laboratory standard for more than 40 years *Over 400 volumes strong *Also available on ScienceDirect.
Nomenclature for mammalian soluble glutathione transferases -- Human alpha class glutathione s-transferases: genetic polymorphism, expression, and susceptibility to disease -- Regulation of GST-P gene expression during hepatocarcinogenesis -- Human glutathione transferase zeta -- Characterization of the omega class of glutathione transferases -- Alternative splicing of glutathione s-transferases -- Disruption of the glutathione transferase pi class genes -- Microsomal glutathione transferase 1 -- Human microsomal prostaglandin E synthase 1: a member of the MAPEG protein superfamily -- Two-dimensional crystallization and electron crystallography of MAPEG proteins -- Plant glutathione transferases -- Phylogenies of glutathione transferase families -- Drosophila glutathione S-transferases -- Mosquito glutathione transferases -- Glutathione S-transferase from malarial parasites: structural and functional aspects -- Optimizing the heterologous expression of glutathione transferase -- Human glutathione transferase A3-3 active as steroid double-bond isomerase -- A subclass of mu glutathione S-transferases selectively expressed in testis and brain -- Glutathione S-transferases as regulators of kinase pathways and anticancer drug targets -- Modification of N-acetyltransferases and glutathione S-transferases by coffee components: possible relevance for cancer risk -- Activation of alkyl halides by glutathione transferases -- Peptide phage display for probing GST-protein interactions -- Fosfomycin resistance proteins, a nexus of glutathione transferases and epoxide hydrolases in a metalloenzyme superfamily -- Regulation of 4-hydroxynonenal mediated signaling by glutathione S-transferases -- Gene expression of c-glutamyltranspeptidase -- c-glutamyltranspeptidase: disulfide bridges, propeptide cleavage, and activation in the endoplasmic reticulum -- Gamma-glutamyl transpeptidase substrate specificity and catalytic mechanism -- c-glutamyl transpeptidase in glutathione biosynthesis -- Prooxidant reactions promoted by soluble and cell-bound c-glutamyltransferase activity.
Includes bibliographical references and index.
San Diego, California : Elsevier Academic Press, ©2005