Pertussis : epidemiology, immunology, and evolution /

Pertussis, or whooping cough, is a respiratory disease caused primarily by infection with the bacterium Bordetella pertussis. It remains among the leading causes of death amongst vaccine-preventable diseases worldwide and recent years have seen its alarming re-emergence in many regions (including th...

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Bibliographic Details
Other Authors: Rohani, Pejman (Editor), Scarpino, Samuel V. (Editor)
Format: eBook
Language:English
Published: Oxford, United Kingdom : Oxford University Press, 2019.
Edition:First edition.
Series:Ecology and evolution of infectious diseases series.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Prologue: the pertussis problem
  • Introduction to pertussis transmission and epidermiological dynamics
  • Basics of pertussis pathogenesis
  • The immunology of Bordetalla pertussis infection and vaccination
  • Pertussis epidemiology
  • Role of vaccine schedules
  • Animal models
  • The human immune responses to pertussis and pertussis vaccines
  • Evolutionary epidemiology theory of vaccination
  • Temporal patterns of Bordetella pertussis genome sequence and structural evolution
  • Vaccine-driven selection and the changing molecular epidemiology of Bordetella pertussis
  • Congenerics: what can be learned about pertussis from pertussis-like disease caused by other Bordetella?
  • Surveillance and diagnostics
  • Contrasting ecological and evolutionary signatures of whooping cough epidemiological dynamics
  • Pertussis immunity and the epidemiological impact of adult transmission: statistical evidence from Sweden and Massachusetts
  • Public health consequences
  • Epilogue: the road ahead
  • Index.