Macromolecular crystallization and crystal perfection /

Structural biology is key to our understanding of the mechanisms of biological processes. This text describes current methods and future frontiers in crystal growth and use of X-ray and neutron crystallography, in the context of automation of crystallization and generation of synchrotron X-ray and n...

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Bibliographic Details
Main Authors: Chayen, Naomi E. (Author), Helliwell, John R. (Author), Snell, Edward H. (Author)
Format: eBook
Language:English
Published: Oxford ; New York : Oxford University Press, 2010.
Series:International Union of Crystallography monographs on crystallography ; 24.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Introduction
  • Crystallization theory
  • Practical methods of crystallization
  • Screening
  • Optimization
  • Strategies to apply when highquality crystals cannot be obtained
  • Membrane proteins
  • Alternative approaches
  • Experimental aspects
  • Analysis of the molecular shortrange order
  • Analysis of longrange order
  • Macromolecular crystals and twinning
  • Other macromolecular crystal diffraction disorders
  • Degradation and improvement of crystal perfection
  • Unusual diffraction geometries
  • Making the most of difficult crystals : beamline and detector optimization
  • Protein powders making the most of tiny crystallites in bulk
  • Complementary techniques
  • The Xray laser and the single molecule no crystal needed?
  • Overall summary and future thoughts.