Human genetic diversity : functional consequences for health and disease /

The secrets of our genetic heritage are finally being unlocked. The massive scientific effort to sequence the human genome is in fact just the beginning of a long journey as the extraordinary genetic diversity that exists between individuals becomes clear. Work in this field promises much: to unders...

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Bibliographic Details
Main Author:	Knight, Julian C.
Format:	eBook
Language:	English
Published:	Oxford ; New York : Oxford University Press, 2009.
Subjects:	Human genetics > Variation. Human molecular genetics. Human evolution. Molecular evolution. Genetic Variation Evolution, Molecular Variabilité génétique. Génétique moléculaire humaine. Êtres humains > Évolution. Évolution moléculaire. HEALTH & FITNESS > Diseases > Genetic. MEDICAL > Genetics. Molecular evolution Human evolution Human genetics > Variation Human molecular genetics Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

Preface; Acknowledgements; 1 Lessons from haemoglobin; 2 Finding genes and specific genetic variants responsible for disease; 3 Cytogenetics and large scale structural genomic variation; 4 Copy number variation in health and susceptibility to disease; 5 Submicroscopic structural variation and genomic disorders; 6 Segmental duplications and indel polymorphisms; 7 Tandem repeats; 8 Mobile DNA elements; 9 SNPs, HapMap, and common disease; 10 Fine scale sequence diversity and signatures of selection; 11 Genetics of gene expression.