Human genetic diversity : functional consequences for health and disease /

The secrets of our genetic heritage are finally being unlocked. The massive scientific effort to sequence the human genome is in fact just the beginning of a long journey as the extraordinary genetic diversity that exists between individuals becomes clear. Work in this field promises much: to unders...

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Bibliographic Details
Main Author: Knight, Julian C.
Format: eBook
Language:English
Published: Oxford ; New York : Oxford University Press, 2009.
Subjects:
Online Access:Connect to the full text of this electronic book

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100 1 |a Knight, Julian C.  |1 https://id.oclc.org/worldcat/entity/E39PCjD7cg6dY9Xwtm4vPj9TwP 
245 1 0 |a Human genetic diversity :  |b functional consequences for health and disease /  |c Julian C. Knight. 
260 |a Oxford ;  |a New York :  |b Oxford University Press,  |c 2009. 
300 |a 1 online resource (xix, 480 pages) :  |b illustrations, maps 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
505 0 |a Preface; Acknowledgements; 1 Lessons from haemoglobin; 2 Finding genes and specific genetic variants responsible for disease; 3 Cytogenetics and large scale structural genomic variation; 4 Copy number variation in health and susceptibility to disease; 5 Submicroscopic structural variation and genomic disorders; 6 Segmental duplications and indel polymorphisms; 7 Tandem repeats; 8 Mobile DNA elements; 9 SNPs, HapMap, and common disease; 10 Fine scale sequence diversity and signatures of selection; 11 Genetics of gene expression. 
520 |a The secrets of our genetic heritage are finally being unlocked. The massive scientific effort to sequence the human genome is in fact just the beginning of a long journey as the extraordinary genetic diversity that exists between individuals becomes clear. Work in this field promises much: to understand our evolutionary origins, to define us as individuals, to predict our risk of disease and to more effectively understand, treat and prevent illness. Contemporary genetic research isallowing the basis of both rare inherited disorders and common multifactorial diseases like asthma and diabetes to. 
650 0 |a Human genetics  |x Variation. 
650 0 |a Human molecular genetics. 
650 0 |a Human evolution. 
650 0 |a Molecular evolution. 
650 1 2 |a Genetic Variation 
650 2 2 |a Evolution, Molecular 
650 6 |a Variabilité génétique. 
650 6 |a Génétique moléculaire humaine. 
650 6 |a Êtres humains  |x Évolution. 
650 6 |a Évolution moléculaire. 
650 7 |a HEALTH & FITNESS  |x Diseases  |x Genetic.  |2 bisacsh 
650 7 |a MEDICAL  |x Genetics.  |2 bisacsh 
650 7 |a Molecular evolution  |2 fast 
650 7 |a Human evolution  |2 fast 
650 7 |a Human genetics  |x Variation  |2 fast 
650 7 |a Human molecular genetics  |2 fast 
655 7 |a Electronic books.  |2 local 
776 0 8 |i Print version:  |a Knight, Julian C.  |t Human genetic diversity.  |d Oxford ; New York : Oxford University Press, 2009  |z 9780199227709  |w (DLC) 2009014872  |w (OCoLC)308218627 
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