Aging of the genome : the dual role of DNA in life and death /

Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible unive...

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Bibliographic Details
Main Author: Vijg, Jan
Format: eBook
Language:English
Published: Oxford ; New York : Oxford University Press, 2007.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology. - ;Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technol.
Physical Description:1 online resource (x, 372 pages) : illustrations
Bibliography:Includes bibliographical references (pages 309-351) and index.
ISBN:9780191524585
0191524581
9781429469937
1429469935
0198569238
9780198569237
0191728241
9780191728242
9786611145255
6611145257