http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Can precision medicine be personal, can personalized medicine be precise?
1 online resource (xvii, 321 pages) : illustrations (black and white, and colour)
"In the medicine of the fifty years, the prevailing paradigms were the ‘biopsychosocial model' and ‘evidence-based medicine'. The currently emerging vision is ‘personalized/precision medicine'. The two interchangeable names—personalized medicine and precision medicine—raise fundamental questions. Is increased precision an improvement in the personal aspects of care or does it risk an erosion of privacy? Do ‘precise' and ‘personalized' approaches marginalize public health? What are the roles of culture and society in the process of personalization? How can personalized medicine's focus on the differences among individuals contribute to the global enterprise of health? In this project, scientists who are leading the revolution of personalized medicine are engaged with clinicians, ethicists, and experts in sociology of medicine and medical law in the search for a common language, elucidating and discussing the moral and social dimensions of personalized/precision medicine. The result is diverse layers of critical analysis and insights. The book contains eighteen chapters. The opening chapters map the horizon of the discourse, articulating the vision and practice of personalized medicine in the contexts of the history of ideas, philosophy of science, and global health. The subsequent chapters explicate specific topics: genetic newborn screening, rare diseases, disorders of consciousness, gender, the clinical encounter, public health, and CRISPR. The concluding chapters offer critical reflections by academic science and technology studies, and by religious traditions. The book concludes by presenting an up-to-date overview from the perspective of research and development"--Publisher's description.
Precision and persons in medicine: a introduction / Yechiel Michael Barilan and Margherita Brusa -- The historical background of personalized medicine / Diego Gracia Guillén -- What 21st century medicine should be - history, vision, implementation, and opportunities / Leroy Hood et al. -- The problematic side of precision medicine: a short voyage through some questions / Giovanni Boniolo -- The precision paradox: how pwersonalized medicine increases uncertainty / Henrik Vogt -- Genomics and precision medicine: through a different prism / Farhat Moazam -- Personalization, individuation, and the ethos of precision medicine / Yechiel Michael Barilan -- Personalized medicine and genetic newborn screening / Margherita Brusa and Donna Dickenson -- The revolution of personalized medicine is already upon us in rare diseases / Christopher P. Austin -- Personalized medicine and disorders of consciousness: an alternate convergence of knowledge towards a new clinical nosology / Joseph J. Fins -- Gender and personalized medicine: methodological and ethical pitfalls / Marianne J. Legato -- Potential challenges to doctor-patient trust posed by personalized medicine / Shlomo Cohen -- When does precision matter? Personalized medicine from the perspective of public health / James Wilson -- CRISPR - a challenge for national and international regulation / Dianne Nicol -- The advent of automated medicine? The values and meanings of precision / Barbara Prainsack -- Thoughtful genomics / Jenny Reardon -- Islamic Sunni perspectives on the ethics of precision medicine / Mehrunisha Suleman -- Genetics, genetic profiles, and Jewish law / Yehoshua Weissinger and Yechiel Michael Barilan -- Pharmaceutical contributions to personalized medicine / Roger Perlmutter.
edited by Yechiel Michael Barilan, Margherita Brusa and Aaron Ciechanover.
This edition also issued in print: 2022.
Includes bibliographical references and index.