http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
molecular approaches toward targeted drug development
1 online resource (xxi, 528 pages : : illustrations (some color.)
Machine generated contents note: pt. One Screening, Bioinformatics, Chemoinformatics, and Drug Design -- 1.Drug Discovery Approaches Toward Anti-Parasitic Agents / Paul M. Selzer -- 2.New Bioinformatic Strategies Against Apicomplexan Parasites / Ke Xiao -- 3.Sorting Potential Therapeutic Targets in Apicomplexa / Gisbert Schneider -- 4.Alternatives to Drug Development in the Apicomplexa / Theo P.M. Schetters -- pt. Two Metabolic Pathways and Processes Addressed by Current Drug-Discovery Approaches -- 5.Energy Metabolism as an Antimalarial Drug Target / Katja Becker -- 6.Polyamines in Apicomplexan Parasites / Rolf D. Walter -- 7.The Reducing Milieu of Parasitized Cells as a Target of Antimalarial Agents: Methylene Blue as an Ethical Drug / R. Heiner Schirmer -- 8.Lipids as Drug Targets for Malaria Therapy / Suzanne Peyrottes -- 9.Targeting Apicoplast Pathways in Plasmodium / Saman Habib
Note continued: 10.Lipoic Acid Acquisition and Glutathione Biosynthesis in Apicomplexan Parasites / Sylke Muller -- 11.Antimalarial Drugs and Molecules Inhibiting Hemozoin Formation / Sumanta Dey -- 12.Exploiting the Vitamin Metabolism of Apicomplexa as Drug Targets / Ingrid B. Muller -- 13.Vitamin Biosynthetic Pathways, the PLP Synthase Complex, and the Potential for Targeting Protein-Protein Interaction / Irmgard Sinning -- 14.Targeting Prokaryotic Enzymes in the Eukaryotic Pathogen Cryptosporidium / Lizbeth Hedstrom -- pt. Three Drug Targets in Apicomplexan Parasites -- 15.Novel Apicomplexan Phosphatases and Immunophilins as Domain-Specific Drug Targets / Sailen Barik -- 16.Dehydrogenases and Enzymes of the Mitochondrial Electron Transport Chain as Anti-Apicomplexan Drug Targets / Katja Becker -- 17.Calcium-Dependent Protein Kinases as Drug Targets in Apicomplexan Parasites / Barbara Kappes
Note continued: 18.Protein Acylation: New Potential Targets for Intervention Against the Apicomplexa / Dominique Soldati-Favre -- 19.Drugs and Drug Targets in Neospora caninum and Related Apicomplexans / Andrew Hemphill -- pt. Four Compounds -- 20.Subversive Substrates of Glutathione Reductases from Plasmodium falciparum-Infeted Red Blood Cells as Antimalarial Agents / Don Antoine Lanfranchi -- 21.Ferroquine: A Concealed Weapon / Daniel Dive -- 22.Current Aspects of Endoperoxides in Antiparasitic Chemotherapy / Katja Becker -- 23.Plasmodium Hsp90 as an Antimalarial Target / Sailen Barik -- 24.Drug Discovery Against Babesia and Toxoplasma / Ikuo Igarashi -- 25.Search for Drugs and Drug Targets against Babesia bovis, Babesia bigemina, Babesia caballi, and Babesia (Theileria) equi / Sabine Bork-Mimm -- 26.Orlistat: A Repositioning Opportunity as a Growth Inhibitor of Apicomplexan Parasites? / Paul M. Selzer
Includes bibliographical references and index.
Drug discovery in infectious diseases ; v. 2