Mechanisms of lymphocyte activation and immune regulation VIII : autoimmunity 2000 and beyond /
Advances in biochemistry, cell biology, genome-wide mutagenesis -- coupled with molecular technology, including gene microarray and transgenic and knock-out animals -- have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases. The...
| Other Authors: | |
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| Format: | Book |
| Language: | English |
| Published: |
New York :
Kluwer Academic/Plenum,
©2001.
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| Series: | Advances in experimental medicine and biology ;
v. 490. |
| Subjects: | |
| Online Access: | Table of contents Publisher description |
| Summary: | Advances in biochemistry, cell biology, genome-wide mutagenesis -- coupled with molecular technology, including gene microarray and transgenic and knock-out animals -- have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases. The molecular definition of these pathways and processes has led to novel treatments for certain auto-immune diseases that are based on the pathogenesis of diseases rather than on broad-spectrum immunosuppression. This book reviews many of these current developments and proposes future novel approaches for understanding the pathogenesis of auto-immune diseases and designing novel therapy. This book covers three major areas of auto-immunity: the basic mechanisms of immunological tolerance, pathogenesis of auto-immune diseases, and some novel therapies. |
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| Physical Description: | viii, 136 pages : illustrations ; 26 cm. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 0306465701 9780306465703 |