Optimal control applied to biological models /
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| Format: | eBook |
| Language: | English |
| Published: |
Boca Raton :
Chapman & Hall/CRC,
©2007.
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| Series: | Chapman and Hall/CRC mathematical & computational biology series.
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- 1 Basic Optimal Control Problems 1
- 1.2 The Basic Problem and Necessary Conditions 7
- 1.3 Pontryagin's Maximum Principle 12
- 2 Existence and Other Solution Properties 21
- 2.1 Existence and Uniqueness Results 23
- 2.2 Interpretation of the Adjoint 26
- 2.3 Principle of Optimality 28
- 2.4 The Hamiltonian and Autonomous Problems 31
- 3 State Conditions at the Final Time 37
- 3.1 Payoff Terms 37
- 3.2 States with Fixed Endpoints 41
- 4 Forward-Backward Sweep Method 49
- 5 Lab 1: Introductory Example 57
- 6 Lab 2: Mold and Fungicide 63
- 7 Lab 3: Bacteria 67
- 8 Bounded Controls 71
- 8.1 Necessary Conditions 73
- 8.2 Numerical Solutions 81
- 9 Lab 4: Bounded Case 85
- 10 Lab 5: Cancer 89
- 11 Lab 6: Fish Harvesting 93
- 12 Optimal Control of Several Variables 97
- 12.1 Necessary Conditions 97
- 12.2 Linear Quadratic Regulator Problems 104
- 12.3 Higher Order Differential Equations 107
- 12.4 Isoperimetric Constraints 108
- 12.5 Numerical Solutions 112
- 13 Lab 7: Epidemic Model 117
- 14 Lab 8: HIV Treatment 123
- 15 Lab 9: Bear Populations 129
- 16 Lab 10: Glucose Model 135
- 17 Linear Dependence on the Control 139
- 17.1 Bang-Bang Controls 139
- 17.2 Singular Controls 143
- 18 Lab 11: Timber Harvesting 153
- 19 Lab 12: Bioreactor 157
- 20 Free Terminal Time Problems 163
- 20.1 Necessary Conditions 163
- 20.2 Time Optimal Control 168
- 21 Adapted Forward-Backward Sweep 175
- 21.1 Secant Method 175
- 21.2 One State with Fixed Endpoints 177
- 21.3 Nonlinear Payoff Terms 182
- 21.4 Free Terminal Time 183
- 21.5 Multiple Shots 184
- 22 Lab 13: Predator-Prey Model 189
- 23 Discrete Time Models 193
- 23.1 Necessary Conditions 193
- 23.2 Systems Case 199
- 24 Lab 14: Invasive Plant Species 205
- 25 Partial Differential Equation Models 211
- 25.1 Existence of an Optimal Control 212
- 25.2 Sensitivities and Necessary Conditions 213
- 25.3 Uniqueness of the Optimal Control 215
- 25.4 Numerical Solutions 215
- 25.5 Harvesting Example 216
- 25.6 Beaver Example 220
- 25.7 Predator-Prey Example 223
- 25.8 Identification Example 228
- 25.9 Controlling Boundary Terms 231
- 26 Other Approaches and Extensions 237.