Pharmacokinetics and toxicokinetics /
The Influence of Routes of Administration on ADMEIntroductionPharmacokinetics (PK) and Pharmacodynamics (PD)Toxicokinetics (TK) and Toxicodynamics (TD)Concepts Basic to PK and TKInfluence of Routes of Exposure/Administration on PK/TK analysisBiomarkersReferencesMechanisms of Absorption and Permeatio...
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| Format: | eBook |
| Language: | English |
| Published: |
Boca Raton, FL :
CRC Press LLC,
[2015]
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | The Influence of Routes of Administration on ADMEIntroductionPharmacokinetics (PK) and Pharmacodynamics (PD)Toxicokinetics (TK) and Toxicodynamics (TD)Concepts Basic to PK and TKInfluence of Routes of Exposure/Administration on PK/TK analysisBiomarkersReferencesMechanisms of Absorption and Permeation of XenobioticsIntroductionPassive DiffusionCarrier-Mediated Transcellular DiffusionTranscellular Diffusion Subject to P-Glycoprotein EffluxActive TransportEndocytosis and PinocytosisSolvent Drag, Osmosis, and Two-Pore TheoryIon-Pair AbsorptionReferencesIn Vivo Distribution of XenobioticsIntroducti. |
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| Physical Description: | 1 online resource |
| Bibliography: | Includes bibliographical references. |
| ISBN: | 9781482221350 1482221357 |