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Forensic applications of high performance liquid chromatography
1 online resource (xvii, 253 pages, 4 unnumbered pages of plates) : illustrations (some color)
"Forensic Applications of High Performance Liquid Chromatography uses real-life examples likely to be found within a forensic science laboratory to explain HPLC from a forensic perspective." "The book presents key point summaries and questions to enhance learning and test comprehension, provides a complete glossary of terms, and includes references at the end of each chapter to facilitate further study. An invaluable guide for those in the early stages of their forensic analysis careers, this volume is also suitable as a textbook for university students studying analytical chemistry, applied chemistry, forensic chemistry, or other courses with an element of HPLC within the course curriculum."--Jacket
Introduction to HPLC The History of Chromatography; Basic Instrumentation -- Basic Principles of HPLC: Theory of Chromatography; Chemical Bonding and Polarity -- Mobile Phase Preparation, the Use of Buffers, and Sample Preparation: Mobile Phase Preparation; Buffers; Sample and Standard Preparation -- Modes of Separation: Reverse Phase HPLC; Ion Exchange; Normal Phase HPLC -- Detection Systems: Theory; UV/Vis Detectors versus Diode Array Detectors; Electrochemical Detectors; Mass Spectrometry -- Method Development in Reversed Phase HPLC: Sample Composition; Which Column Will Affect the Separation?; Choosing a Mobile Phase; Automated Method Development; Method Development Strategy; Method Development Worked Example -- System Suitability -- System Performance; Chromatographic Suitability -- Qualification, Validation, and Verification: Valid Analytical Measurement ; Estimation of Uncertainty of Measurement, Sources of Error, and Statistical Evaluation; Instrument Qualification; Method Validation; Method Verification -- Quality Systems: What Is Quality?; Introduction to Quality Assurance; How Do We Ensure Quality in Our Laboratories?; A Quality Management System; Accreditation; Auditing -- Troubleshooting HPLC Systems: Troubleshooting; Tool Kit and Spare Parts; Preventative Maintenance; Column Care -- Forensic Applications of HPLC: Drug Analysis; Toxicological Analysis; Colour Analysis; Analysis of Explosives; Food and the Environment.
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL
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Includes bibliographical references and index.
Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. WlAbNL
Boca Raton : CRC Press/Taylor & Francis, ©2010
Analytical Concepts in Forensic Chemistry