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Predicting solubility of new drugs : handbook of critically curated data for pharmaceutical research /

"In pharmaceutical research, solubility plays a key part in the assessment of pharmacokinetic risks. Poor drug absorption, reduced efficacy, excessive metabolism and adverse reactions are frequently related to issues of drug solubility. During early discovery research at pharmaceutical companie...

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Bibliographic Details
Main Author: Avdeef, Alex (Author)
Format: eBook
Language:English
Published: Boca Raton : CRC Press, [2024]
Edition:First edition.
Subjects:
Drugs > Solubility > Handbooks, manuals, etc.
Drugs > Metabolism > Handbooks, manuals, etc.
Drugs > Design > Handbooks, manuals, etc.
Drug development > Handbooks, manuals, etc.
Solubility.
Pharmaceutical Preparations > analysis.
Pharmaceutical Preparations > metabolism.
Handbook.
Online Access:Connect to the full text of this electronic book.
Table of Contents:
  • Introduction
  • Physiochemical properties of Wiki-pS0 database molecules
  • Solubility prediction methods
  • Predicting solubility of PROTACs
  • Predicting solubility of new drugs
  • Instruments with 'intelligence.'