Parameters for pesticide QSAR and PBPK/PD models for human risk assessment /

Bibliographic Details
Corporate Authors:	American Chemical Society, American Chemical Society. Division of Agrochemicals
Other Authors:	Knaak, James B., Timchalk, Charles, Tornero-Velez, Rogelio
Format:	eBook
Language:	English
Language Notes:	English.
Published:	Washington, DC : American Chemical Society, ©2012.
Series:	ACS symposium series ; 1099.
Subjects:	Chemical models > Congresses. Pharmacokinetics > Congresses. Risk assessment > Congresses. Risk. Structure-activity relationships (Biochemistry) Agricultural chemicals. Mathematical models. Risk management. Metabolism. Probabilities. Organization. Public health. Health services administration. Statistics. Medical care. Pesticides. Risk assessment. QSAR (Biochemistry) Pharmacokinetics. Chemical models. Risk Structure-Activity Relationship Agrochemicals Models, Theoretical Risk Management Toxic Actions Pharmacological Phenomena Publication Formats Epidemiologic Measurements Kinetics Specialty Uses of Chemicals Metabolism Chemical Actions and Uses Probability Biochemical Phenomena Organization and Administration Phenomena and Processes Publication Characteristics Public Health Physiological Phenomena Investigative Techniques Environment and Public Health Health Services Administration Chemical Phenomena Chemicals and Drugs Statistics as Topic Analytical, Diagnostic and Therapeutic Techniques and Equipment Health Care Evaluation Mechanisms Epidemiologic Methods Delivery of Health Care Quality of Health Care Health Care Quality, Access, and Evaluation Pesticides Risk Assessment Quantitative Structure-Activity Relationship Pharmacokinetics Models, Chemical Congresses Patient Care Management Patient Care Management > methods Patient Care Modèles chimiques > Congrès. Pharmacocinétique > Congrès. Évaluation du risque > Congrès. Risque. Relations structure-activité (Biochimie) Produits chimiques agricoles. Modèles mathématiques. Gestion du risque. Métabolisme. Probabilités. Organisation. Santé publique. Services de santé > Administration. Statistiques. Prestation de soins. Évaluation du risque. Relations structure-activité quantitatives (Biochimie) Pharmacocinétique. Modèles chimiques. Statistique. Soins médicaux. mathematical models. risk management. metabolism (biological concept) probability. public health. pesticide. risk assessment. statistics. MEDICAL > Pharmacology. Statistics Risk management Public health Probabilities Organization Medical care Mathematical models Health services administration Agricultural chemicals Chemical models Risk assessment Electronic books. Congress proceedings (reports) Conference papers and proceedings Conference papers and proceedings. Actes de congrès.
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Table of Contents:

Parameters for pesticide QSAR and PBPK/PD models to inform human risk assessments
Chiral chemistry and toxicity assessments for pyrethroid pesticides
Direct chiral separation of pyrethroid isomers by HPLC with chiral stationary phases
Biotransformation and enzymes responsible for metabolism of pyrethroids in mammals
Characterization of potential age-related differences in pyrethroid pharmacokinetics
15 factors of percutaneous penetration of pesticides
Percutaneous absorption of pesticide formulations
Human metabolic interactions of pesticides : inhibition, induction and activation
Paraoxonase 1 (PON1) status in risk assessment for organophosphate exposure and pharmacokinetics
Carboxylesterases : a multifunctional enzyme involved in pesticide and lipid metabolism
Behavioral changes in adult and young rats as indications of cholinesterase inhibition
Comparison of esterase sensitivity, metabolic efficiency, and toxicity levels of two organophosphorus insecticides, parathion and chlorpyrifos
Regional brain dosimetry for the organophosphorus insecticide chlorpyrifos in the preweanling rat
Pyrethroid actions on sodium channels : isoform and species specificity
In vitro and in vivo experimental data for development and use of pharmacokinetic models for in vitro to in vivo extrapolation of pyrethroid insecticides
In silico strategies for modeling stereoselective metabolism of pyrethroids
Quantitative structure-activity relationships for organophosphate enzyme inhibition
Computational approaches for developing informative prior distributions for bayesian calibration of PBPK models
Use of cytochrome P450-specific parameters and human biomarker data to develop a human physiologically based pharmacokinetic/pharmacodynamic model for dermal chlorpyrifos exposure
Use of in vitro data in PBPK models : an example of in vitro to in vivo extrapolation with carbaryl.