Table of Contents:
  • Pro-drugs : an overview and definition / V. Stella
  • Application of the pro-drug approach to antibiotics / A.A. Sinkula
  • The chemistry of a novel 5,5-diphenylhydantoin pro-drug / V. Stella, T. Higuchi, A. Hussain, and J. Truelove
  • The metabolic disposition of a novel 5,5-diphenylhydantoin pro-drug / A.J. Glazko, W.A. Dill, R.H. Wheelock, R.M. Young, A. Nemanich, L. Croskey, V. Stella, and T. Higuchi
  • Case histories of the development of pro-drugs for use in the formulation of cytotoxic agents in parenteral solutions / Arnold J. Repta
  • The effect of a pro-drug of epinephrine (dipivalyl epinephrine) in glaucoma : general pharmacology, toxicology, and clinical experience / David A. McClure.