Table of Contents:
  • Carbohydrates : synthetic methods and applications in antisense therapeutics : an overview / Yogesh S. Sanghvi and P. Dan Cook
  • Novel backbone replacements for oligonucleotides / Alain De Mesmaeker, Adrian Waldner, Jacques Lebreton, Valérie Fritsch, and Romain M. Wolf
  • Synthesis of nonionic oligonucleotide analogues / Joseph A. Maddry, Robert C. Reynolds, John A. Montgomery, and John A. Secrist, III
  • Synthesis and hybridization properties of DNA oligomers containing sulfide-linked dinucleosides / George Just and Stephen H. Kawai
  • 4'-thio-RNA : a novel class of sugar-modified [beta]-RNA / Laurent Bellon, Claudine Leydier, Jean-Louis Barascut, Georges Maury, and Jean-Louis Imbach
  • Hexopyranosyl-like oligonucleotides / Piet Herdewijn, Hans De Winter, Bogdan Doboszewski, Ilse Verheggen, Koen Augustyns, Chris Hendrix, Tula Saison-Behmoaras, Camiel De Ranter, and Arthur Van Aerschot
  • [Alpha]-bicyclo-DNA : synthesis, characterization, and pairing properties of [alpha]-DNA-analogues with restricted conformational flexibility in the sugar-phosphate backbone / M. Bolli, P. Lubini, M. Tarköy, and C. Leumann
  • 2',5'-oligoadenylate antisense chimeras for targeted ablation of RNA / Paul F. Torrence, Wei Xiao, Guiying Li, Krystyna Lesiak, Shahrzad Khamnei, Avudaiappan Maran, Ratan Maitra, Beihua Dong, and Robert H. Silverman
  • Branched nucleic acids : synthesis and biological applications / R.H.E. Hudson, K. Ganeshan, and M.J. Damha
  • Anti-human immunodeficiency virus activity and mechanisms of unmodified and modified antisense oligonucleotides / T. Hatta, S.-G. Kim, S. Suzuki, K. Takaki, and H. Takaku
  • Carboranyl oligonucleotides for antisense technology and boron neutron capture therapy of cancers / Raymond F. Schinazi, Zbigniew J. Lesnikowski, Géraldine Fulcrand-El Kattan, and David W. Wilson
  • Advances in automated chemical synthesis of oligoribonucleotides / Nanda D. Sinha and Stephen Fry
  • Anti-human immunodeficiency virus activity of a novel class of thiopurine-based oligonucleotides / Rich B. Meyer, Jr., Alexander A. Gall, and Vladimir V. Gorn
  • New twists on nucleic acids : structural properties of modified nucleosides incorporated into oligonucleotides / Richard H. Griffey, Elena Lesnik, Susan Freier, Yogesh S. Sanghvi, Kelly Teng, Andrew Kawasaki, Charles Guinosso, Patrick Wheeler, Ventrankaman Mohan, and P. Dan Cook.