Inosine monophosphate dehydrogenase : a major therapeutic target /
Annotation
| Other Authors: | , |
|---|---|
| Format: | eBook |
| Language: | English |
| Language Notes: | English. |
| Published: |
Washington, D.C. :
American Chemical Society : Distributed by Oxford University Press,
©2003.
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| Series: | ACS symposium series ;
839. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Inosine Monophosphate Dehydrogenase and Its Inhibitors: An Overview / Pankiewicz, Krzysztof W., Pharmasset, Incorporated, 1860 Montreal Road, Tucker, GA 30084 (email: kpankiewicz@pharmasset.com); Goldstein, Barry M., Department of Biochemistry and Biophysics, University of Rochester Medical Center, 901 Elmwood Avenue, Rochester, NY 14642 (email: barry_goldstein@urmc.rochester.edu)
- IMP, DH, and GTP: Linkage with Neoplasia, Target of Chemotherapy, Regulation of Ras, Signal Transduction, and Apoptosis / Weber, George
- Biological Significance of Guanylate Synthesis and IMP Dehydrogenase Isoforms / Natsumeda, Yutaka
- An Emerging Cell Kinetics Regulation Network: Integrated Control of Nucleotide Metabolism and Cancer Gene Function / Sherley, James L.
- Targeted Disruption of the IMPDH: Type II Gene: Effect on Mouse Development and Lymphocyte Activation / Gu, Jing Jin, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599; Stegmann, Sander, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599; Mitchell, Beverly S., Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, Departments of Medicine and Pharmacology, University of North Carolina, Chapel Hill, NC 27599
- Differential Splicing of Pneumocystis carinii Inosine 5'-Monophosphate Dehydrogenase mRNA: Implications for Producing Catalytically Active Protein / Ye, Dongjiu; Nott, Jeniece; Queener, Sherry F.
- IMPDH Structure and Ligand Binding / Goldstein, Barry M., Corresponding author: telephone: 716-275-5095; fax: 716-275-6007; email: barry.goldstein@rochester.edu; Risal, Dipesh; Strickler, Michael
- Monovalent Cation Activation of IMP Dehydrogenase / Markham, George D.
- IMP Dehydrogenase: Mechanism of Drug Selectivity / Hedstrom, Lizbeth, Department of Biochemistry, MS 009, Brandeis University, Waltham, MA 02454; Digits, Jennifer A., Department of Biochemistry, MS 009, Brandeis University, Waltham, MA 02454, Current address: Department of Pharmacology and Cancer Biology, Duke University Medical Center, Levine Science and Research Center, Box 3686, Durham, NC 27710, Supported by National Institutes of Health Molecular Structure and Function Training Grant GM07956 (J.A.D.), NIH GM54403 (L.H.) and a grant from the Markey Charitable Trust to Brandeis University
- The Discovery of Thiazole-4-Carboxamide Adenine Dinucleotide (TAD) and a Recent Synthetic Approach for the Construction of a Hydrolytically Resistant Surrogate / Marquez, Victor E.
- C-Nucleoside Analogs of Tiazofurin and Selenazofurin as Inosine 5'-Monophosphate Dehydrogenase Inhibitors / Franchetti, P., Dipartimento di Scienze Chimiche, Università di Camerino, Via S. Agostino, 1. 62032 Camerino, Italy; Cappellacci, L., Dipartimento di Scienze Chimiche, Università di Camerino, Via S. Agostino, 1. 62032 Camerino, Italy; Grifantini, M., Dipartimento di Scienze Chimiche, Università di Camerino, Via S. Agostino, 1. 62032 Camerino, Italy; Jayaram, H. N., Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, 635 Barnhill Drive, MS 4053, Indianapolis, IN 46202-5122; Goldstein, B. M., Department of Biochemistry and Biophysics, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642
- Studies with Benzamide Riboside, a Recent Inhibitor of Inosine 5'-Monophosphate Dehydrogenase / Jayaram, Hiremagalur N., Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, 635 Barnhill Drive, MS 4053, Indianapolis, IN 46202-5122; Yalowitz, Joel A., Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, 635 Barnhill Drive, MS 4053, Indianapolis, IN 46202-5122; Krupitza, Georg, University of Vienna, Wahringer Gurtel 18-20, A-1090 Vienna, Austria; Szekeres, Thomas, University of Vienna, Wahringer Gurtel 18-20, A-1090 Vienna, Austria; Krohn, Karsten, Division of Organic Chemistry, Universitat Gesamthochschule Paderborn, Paderborn 1621-4790, Germany; Pankiewicz, Krzysztof W., Pharmasset, Incorporated, 1860 Montreal Road, Tucker, GA 30084
- Cofactor Analogues as Inhibitors of IMP Dehydrogenase: Design and New Synthetic Approaches / Pankiewicz, Krzysztof W., Pharmasset, Incorporated, 1860 Montreal Road, Tucker, GA 30084 (email: kpankiewicz@pharmasset.com or spatterson@pharmasset.com); Patterson, Steven, Pharmasset, Incorporated, 1860 Montreal Road, Tucker, GA 30084 (email: kpankiewicz@pharmasset.com or spatterson@pharmasset.com); Jayaram, Hiremagalur N., Indiana University School of Medicine, Indianapolis, IN 46202 (email: hjayaram@iupui.edu); Goldstein, Barry M., University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642 (email: barry_goldstein@urmc.rochester.edu)
- Identification of Specific Inhibitors of IMP Dehydrogenase / Collart, Frank R., Biosciences Division, 9700 South Cass Avenue, Building G 202, Argonne, IL 60439, Corresponding author: email: Fcollart@anl.gov; telephone: 630-252-4859; fax: 630-252-5517; Huberman, Eliezer, Biochip Technology Center, Argonne National Laboratory, 9700 South Cass Avenue, Building G 202, Argonne, IL 60439
- Mizoribine: Experimental and Clinical Experience / Ishikawa, Hiroaki; Tsuchiya, Masahiko; Itoh, Hiromichi