Table of Contents:
  • pt. 1. General overview
  • Introduction and overview of the aldo-keto reductase superfamily / Trevor M. Penning
  • part 2. Aldo-keto reductases and endogenous toxicants
  • Aldo-keto reductase-catalyzed detoxification of endogenous aldehydes associated with diabetic complications / David L. Vander Jagt
  • Aldose reductase detoxifies lipid aldehydes and their glutathione conjugates / Satish K. Srivastava
  • Role of aldose reductase in the detoxification of oxidized phospholipids / Sanjay Srivastava
  • part 2. Aldo-keto reductases and exogenous toxicants: tobacco-related carcinogens
  • Competing roles of reductases in the detoxification of the tobacco-specific nitrosamine ketone NNK / Edmund Maser
  • Aldo-keto reductases and the metabolic activation of polycyclic aromatic hydrocarbons / Trevor M. Penning
  • Molecular cloning and characterization of dihydrodiol dehydrogenase from the mouse / Yoshihiro Deyashiki
  • Efficient syntheses of the active metabolites of carcinogenic polycyclic aromatic hydrocarbons / Ronald G. Harvey
  • Chemistry of polycyclic aromatic hydrocarbons (PAH) o-Quinones generated by the aldo-keto reductase pathway of PAH activation / Sridhar R. Gopishetty
  • Analysis of etheno 2'-deoxyguanosine adducts as dosimeters of aldo-keto reductase mediated-oxidative stress / Seon Hwa
  • Aldo-keto reductases and exogenous toxicants: mycotoxins, aldehydes, and ketones
  • Aflatoxin aldehyde reductases / Vincent P. Kelly
  • Competing reactions of aflatoxin B1 dialdehyde: enzymatic reduction versus adduction with lysine / F. Peter Guengerich
  • The use of mammalian cell lines to investigate the role of aldo-keto reductases in the detoxification of aldehydes and ketones / Rachel Gardner
  • Aldo-keto reductases, the stress response, and cell signaling
  • Aldose reductase and the stress response / Aruni Bhatnagar
  • Aldose reductase regulates reactive oxygen species mediated-inflammatory signals / Kota V. Ramana
  • Aldo-keto reductases in the stress response of the budding yeast Saccharomyces cerevisiae / Qing Chang.