Conducting systematic review of meta-analyses effectively and efficiently : endpoint surrogacy for overall survival in oncological randomized controlled trials with immunotherapies /
This case discusses a systematic review of meta-analyses, which summarizes results from several meta-analyses. I and colleagues reviewed eligible meta-analyses in an effort to summarize how well the treatment effects in surrogate endpoints like progression-free survival could predict the treatment e...
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| Format: | eBook |
| Language: | English |
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London :
SAGE Publications Ltd.,
2020.
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| Series: | SAGE Research Methods Cases : Medicine and Health.
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | This case discusses a systematic review of meta-analyses, which summarizes results from several meta-analyses. I and colleagues reviewed eligible meta-analyses in an effort to summarize how well the treatment effects in surrogate endpoints like progression-free survival could predict the treatment effects in overall survival, in order to evaluate whether progression-free survival and other surrogate endpoints could be valid enough as a surrogate endpoint for overall survival in oncological randomized controlled trials with immunotherapies. The structure of a systematic review of meta-analyses is almost the same as the structure of a single systematic review and/or meta-analysis, which has been very well described in other works. Therefore, in this case study, I briefly describe the basic steps of conducting a systematic review of systematic reviews and/or meta-analyses. Based on the steps, I provide some of my thoughts about how to conduct a systematic review effectively and efficiently. |
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| Physical Description: | 1 online resource. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9781529744163 1529744164 |