rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Disparities in Treatment Utilization, Delay and Outcomes among Patients with Hepatocellular Carcinoma in the United States
  name:
    name part: Wagle, Nikita Sandeep
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Kum, Hye-Chung
    role:
      role term: thesis advisor.
  name:
    name part: Texas A&M University
    role:
      role term: degree granting institution.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: txu
    date issued: 2023
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource.
  abstract: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death in the United States (US). Racial-ethnic minority groups are at a greater risk of treatment underutilization and delay, along with worse outcomes. Prior published literature in other cancers like lung, colorectal, prostate indicates that social determinants of health (SDOH) like lower neighborhood SES are associated with worse survival. However, the interplay between race, ethnicity, and SDOH has not been well explored among HCC patients. Therefore, this dissertation aims to (1) characterize and quantify racial-ethnic disparities in treatment receipt among patients with HCC through a meta-analysis; (2) characterize the interaction of racial, ethnic, and neighborhood socioeconomic disparities in curative treatment use and overall survival in the US among a large population-based sample of patients with HCC (3) describe the prevalence and disparities in HCC treatment delay and evaluate the association between treatment delay and overall survival in a large population-based sample of patients with HCC in the US. Results from the first study indicate that Black and Hispanic patients had a lower pooled odds ratio (OR) for receipt of curative treatment when compared to White patients. Additionally, Black patients had lower pooled OR for receiving any HCC-specific treatment when compared to White patients. Results from the second study indicate that curative treatment was underutilized among HCC patients. Additionally, Black patients living in high poverty neighborhoods had lower odds of receiving curative treatment and worse survival when compared to white patients living in similar neighborhoods. Results from the third study indicate that Black patients and those living in high poverty neighborhoods had higher odds of receiving delayed treatment. Subsequently, delayed treatment was associated with worse overall survival. Neighborhood poverty level may be a mediating factor adding to persi…
  note: by Nikita Wagle.
  note: "Major Subject: Health Services Research"
  note: Includes vita.
  note: Doctor of Philosophy Texas A&M University 2022 https://hdl.handle.net/1969.1/197227
  note: Includes bibliographical references.
  note: Text (Dissertation)
  subject:
    topic: Major Health Services Research
  subject:
    topic: Liver cancer
  subject:
    topic: Inequity
  subject:
    topic: Treatment
  subject:
    topic: Prognosis.
  identifier: https://hdl.handle.net/1969.1/197227
  record info:
    record content source: TXA
    record creation date: 240819
    record change date: 20240820145854.5
    record identifier: in00005463543
    language of cataloging:
      language term: eng