Phase Separation in Living Cells : Benefits and Risks /

This book presents the latest cutting-edge research on phase separation. It discusses the benefits and risks of phase separation for living cells from the perspectives of physics, chemistry, biology, and medicine. Phase separation is a physico-chemical process that induces a single solution of solve...

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Bibliographic Details
Corporate Author:	SpringerLink (Online service)
Other Authors:	Kurokawa, Riki (Editor)
Format:	eBook
Language:	English
Published:	Singapore : Springer Nature Singapore : Imprint: Springer, 2023.
Edition:	1st ed. 2023.
Subjects:	Molecular biology. Biophysics. Medicine > Research. Biology > Research. Cytology. Biochemistry. Non-coding RNA. Molecular Biology. Biomedical Research. Cell Biology. Non-coding RNAs. Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

Chapter 1. FUS aggregation by shear stress on pipetting and its suppression by non-coding RNA
Chapter 2. Basics and recent advances in computational and theoretical methods for understanding the liquid-liquid phase separation
Chapter 3.Promotion of liquid-liquid phase separation by G-quadruplex DNA and RNA
Chapter 4. Phase regulation by chaperons
Chapter 5. Regulation of aggregation of intrinsically disordered protein through phase separation: Risk management of phase separation
Chapter 6. Molecular mechanisms of phase transition/separation of protein low-complexity sequences
Chapter 7. Winding and Tangling. An Initial Phase of Membrane-less Organelle Formation (from a viewpoint of Cajal Bodies)
Chapter 8. Formation and function of phase separated nuclear bodies directed by architectural noncoding RNA
Chapter 9. Force-dependent remodeling of cell-to-cell adhesion through the regulation of phase separation
Chapter 10. Neuronal RNA granules: Phase separation, dynamics, and higher brain functions
Chapter 11. Liquid-liquid phase separation in structure and function of nuclear pore complex
Chapter 12. Phase Separation Orchestrates Cancer Signaling: Biomolecular condensates as a promising target for cancer therapy
Chapter 13. Regulatory interaction of intrinsically disordered regions of pathogenic proteins in neurodegenerative diseases
Chapter 14. Functional properties of phase separation and intranuclear complex of FUS in the pathogenesis of ALS/FTLD
Chapter 15. Functional responses of microglia to amyloid plaques
Chapter 16. Emerging role of phage separation in COVID-19.