Protecting groups /
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Stuttgart ; New York :
Georg Thieme,
[2004]
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| Edition: | 3rd ed. |
| Subjects: |
Table of Contents:
- Death, Taxes, and Protecting Groups
- Deprotection: The Concept of Orthogonal Sets
- Protecting Groups Cleaved by Basic Solvolysis
- Protecting Groups Cleaved by Acid
- Protecting Groups Cleaved by Heavy Metals
- Protecting Groups Cleaved by Fluoride Ions
- Protecting Groups Cleaved by Reductive Elimination
- Protecting Groups Cleaved by [beta]-Elimination Reactions
- Protecting Groups Cleaved by Hydrogenolysis
- Protecting Groups Cleaved by Oxidation
- Protecting Groups Cleaved by Dissolving Metal Reduction
- Protecting Groups Cleaved by Nucleophilic Substitution
- Protecting Groups Cleaved by Transition Metal Catalysis
- Protecting Groups Cleaved by Light
- Protecting Groups Cleaved by Enzymes
- Relay Deprotection
- Transprotection
- Mutual Protection
- Temporary Protection
- Protecting Groups As Not-So-Innocent Bystanders
- Neighbouring Group Participation
- Conformational and Electronic Effects
- Co-ordination Effects
- Protecting Groups and Solid-Phase Synthesis
- General Reviews on Protecting Groups
- Reviews on Enzyme-Labile Protecting Groups
- Reviews on Photo-Labile Protecting Groups
- Reviews on Linkers in Solid-Phase Synthesis
- Reviews on the Synthesis of Complex Targets Including Discussion of Protecting Group Problems and Strategies
- Carbonyl Protecting Groups
- O, O-Acetals
- Cyclic Acetals
- O, O-Acetals in Asymmetric Synthesis
- Acyclic O, O-Acetals
- S, S-Acetals
- O, S-Acetals
- N, O-Acetals
- Cyanohydrins
- Orthoester Derivatives
- O, O, O-Orthoesters
- O, S, S-Orthoesters.
- S, S, S-Orthoesters
- Oxazolines
- Reviews Concerning the Preparation of O, O-Acetals and Their Use as Protecting Groups
- Reviews Concerning the Mechanism for Hydrolysis of Acetals
- Reviews Concerning O, O-Acetals as Reactive Functionality
- Reviews Concerning the Preparation, Chemistry, and Hydrolysis of O, S- and S, S-Acetals
- Reviews Concerning the Synthesis and Reactions of N, O-Acetals and Their Use in Asymmetric Synthesis
- Reviews Concerning the Chemistry of Orthoesters and Oxazolines
- Diol Protecting Groups
- O, O-Acetals
- Isopropylidene Acetals
- Cyclopentylidene and Cyclohexylidene Acetals
- The Arylmethylene Acetal Family
- Methylene Acetals
- Diphenylmethylene Acetals
- 1,2-Diacetals
- Dispoke Derivatives
- Cyclohexane-1,2-diacetals
- Butane-2,3-diacetals
- Silylene Derivatives
- 1,1,3,3-Tetraisopropyldisiloxanylidene Derivatives
- N, O-Acetals for the Protection of 1,2- and 1,3-Amino Alcohols
- Reviews Concerning the Protection of 1,2- and 1,3-Diols
- Reviews Concerning Acetal Derivatives of Carbohydrates
- Reviews Concerning 1,2-Diacetals
- Reviews Concerning N, O-Acetals
- Hydroxyl Protecting Groups
- Silyl Ethers
- Trimethylsilyl (TMS) Ethers
- Triethylsilyl (TES) Ethers
- tert-Butyldimethylsilyl (TBS) Ethers
- tert-Butyldiphenylsilyl (TBDPS) Ethers
- Triisopropylsilyl (TIPS) Ethers
- Diethylisopropylsilyl (DEIPS) Ethers
- Thexyldimethylsilyl (TDS) Ethers
- Triphenylsilyl (TPS) Ethers
- Di-tert-butylmethylsilyl (DTBMS) Ethers
- Alkyl Ethers
- Methyl Ethers
- tert-Butyl Ethers.
- Benzyl Ethers (Bn)
- p-Methoxybenzyl (PMB) and 3,4-Di-methoxybenzyl (DMB) Ethers
- Trityl (Tr) Ethers
- Allyl Ethers and Allyloxycarbonyl Derivatives
- Alkoxymethyl Ethers
- Methoxymethyl (MOM) Ethers
- 2-Methoxyethoxymethyl (MEM) Ethers
- Benzyloxymethyl (BOM) and Related Ethers
- p-Methoxybenzyloxymethyl (PMBM) Ethers
- 2-(Trimethylsilyl)ethoxymethyl (SER) Ethers
- Tetrahydropyranyl (THP) and Related Ethers
- Methylthiomethyl (MTM) Ethers
- Esters
- Acetate Esters (Ac)
- Benzoate Esters (Bz)
- Pivalate Esters (R)
- Methoxyacetate Esters
- Chloroacetate Esters
- Levulinate Esters (Lev)
- Carbonates
- Benzyl Carbonates (RO-CBz)
- p-Nitrobenzyl Carbonates (RO-CO[subscript 2]PNB)
- tert-Butyl Carbonates (RO-Boc)
- 2,2,2-Trichloroethyl Carbonates (RO-Troc)
- 2-(Trimethylsilyl)ethyl Carbonates (RO-Teoc)
- Allyl Carbonates (RO-Aloc)
- General Reviews Concerning the Protection of Hydroxyls
- Reviews Concerning Enzyme-Mediated Esterification and Hydrolysis of Esters
- Reviews Concerning Organosilicon and Organotin Chemistry Relevant to Hydroxyl Protection
- Thiol Protecting Groups
- Thioether Derivatives
- tert-Butyl Thioethers
- Benzyl and Substituted Benzyl Thioethers
- Trityl (Tr) Thioethers
- 2-(Trimethylsilyl)ethyl (TMSE) Thioethers
- 2-Cyanoethyl Thioethers
- 9-Fluorenylmethyl (Fm) Thioethers
- Thiocarbonate Derivatives
- Disulfides as Protecting Groups and Targets
- Reviews Concerning the Protection of Thiols
- Reviews Concerning the Chemistry of Thiols and Disulfides.
- Carboxyl Protecting Groups
- General Comments on the Esterification of Carboxylic Acids
- Methyl Esters and Derivatives
- Methyl Esters
- tert-Butyl Esters
- Benzyl Esters
- Allyl Esters
- Phenacyl Esters
- Alkoxyalkyl Esters
- Esters Cleaved by [beta]-Elimination Reactions
- 2,2,2-Trichloroethyl Esters
- 2-(Trimethylsilyl)ethyl (TMSE) Esters
- 2-Tosylethyl Esters and Related Base-Labile Groups
- Silyl Esters
- Reviews Concerning the Specific Use of Esters as Protecting Groups
- Reviews Concerning the Preparation of Esters
- Reviews Concerning Techniques for Facilitating Esterification
- Reviews Concerning the Use of Allyl Esters in Carboxyl Protection
- Reviews Concerning the Nucleophilic Cleavage of Esters
- Phosphate Protecting Groups
- The Reaction of Phosphate Esters with Nucleophiles
- Alkyl Esters
- Methyl and Isopropyl Esters
- tert-Butyl Esters
- Benzyl Esters
- Allyl Esters
- 3',5'-Dimethoxybenzoin Esters
- p-Hydroxyphenacyl Esters
- Esters Cleaved by [beta]-Elimination Reactions
- 2-Cyanoethyl Esters
- 9-Fluorenylmethyl Esters
- 2-(Trimethylsilyl)ethyl Esters
- 2-(Methylsulfonyl)ethyl Esters and Related Base-Labile Groups
- 2,2,2-Trichloroethyl Esters
- Reviews Concerning Protection for the Phosphate Group
- Reviews Concerning the Mechanism of Nucleophilic Substitution in Phosphate Esters
- Amino Protecting Groups
- Imides and Amides
- Phthaloyl (Phth) and Tetrachlorophthaloyl (TCP)
- Dithiasuccinyl (Dts)
- Trifluoroacetyl
- Relay Deprotection of N-Acyl Derivatives.
- Carbamates
- Methoxy- and Ethoxycarbonyl
- tert-Butoxycarbonyl (Boc)
- Benzyloxycarbonyl (Z or Cbz)
- Allyloxycarbonyl (Aloc)
- 9-Fluorenylmethoxycarbonyl (Fmoc)
- 2-(Trimethylsilyl)ethoxycarbonyl (Teoc)
- 2,2,2-Trichloroethoxycarbonyl (Troc)
- Sulfonyl Derivatives
- Arylsulfonyl Derivatives
- 2-(Trimethylsilyl)ethylsulfonyl (SES) Derivatives
- N-Sulfenyl Derivatives
- N-Alkyl Derivatives
- N, O-Acetals
- Triazinanones
- Benzyl (Bn) and Diphenylmethyl (Dpm)
- Trityl (Tr) and 9-Phenylfluorenyl (PhFl)
- Allyl
- N-Silyl Derivatives
- Imine and Enamine Derivatives
- N-Bis(methylthio)methylene
- N-Diphenylmethylene
- Special Cases
- Orthogonal Protecting Groups for the Synthesis of Polyamines
- Protecting Groups for Guanidines
- Protecting Groups for Indoles, Pyrroles, and Imidazoles
- General Reviews on Amino Protecting Groups
- Reviews Concerning N-Protection in the Synthesis of [alpha]-Amino Aldehydes and Ketones
- Reviews Concerning N-Protection in the Synthesis of [beta]-Lactams
- Reviews Concerning N-Functional Groups Pertinent to Their Role as Protecting Groups
- Reviews Concerning the Synthesis of Natural Guanidine Derivatives
- Reviews Concerning the Synthesis of Natural Polyamines.