Description
| Abstract: | Dr. Jeff Kelly's laboratory has been using 4-(2-aminoethyl)-6-dibenzofuran propoinic acid an unnatural amino acid to initiate sheet folding. The unnatural amino acid mimics a tum in an antiparallel sheet structure. Peptides that incorporate the dibenzofuran based unnatural amino acid are being used to study the mechanism of folding and the synthesis of novel materials. A new synthesis of 4-(2-aminoethyl)-6-dibenzofuran propoinic acid has been created. The synthesis has a high yield and simple purification. The synthesis is based on the desymmetrization of the dibenzofuran ring using a monosilylation reaction. |
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| Item Description: | Undergraduate thesis written for Program year: 1996/1997 |
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| Physical Description: | Digitized from print version held at Pickle Center High Density Storage, barcode 24829580. |
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