| Abstract: | Mutants of vesicular stomatitis virus (VSV) were generated by treatment during the virus' infective phase with the known frameshift mutagen ICR-191. Both mutant and wild-type viral proteins were labelled with ³⁵ S-methionine, extracted, and examined by SDS-polyacrylamide gel electrophoresis (SDS-PAGE), looking for mutant proteins that exhibited differing mobilities from their corresponding wild-type protein. Two alterred protein products were observed. One involved the G protein while the other involved either the N or NS proteins. |
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