Handbook of applied health economics in vaccines /

Vaccine discovery, financing, and distribution offer technical challenges requiring difficult choices. Patients, parents, providers, and politicians all must decide about who, when, where to vaccinate. Billions if not trillions of dollars and millions of lives depend on getting these choices right....

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Bibliographic Details
Corporate Author: Oxford University Press
Other Authors: Bishai, David (Editor), Brenzel, Logan E. (Editor), Padula, William (Editor)
Format: eBook
Language:English
Published: Oxford : Oxford University Press, 2023.
Edition:First edition.
Series:Handbooks in health economic evaluation series.
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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245 0 0 |a Handbook of applied health economics in vaccines /  |c edited by David Bishai, Logan Brenzel and William V. Padula. 
250 |a First edition. 
264 1 |a Oxford :  |b Oxford University Press,  |c 2023. 
300 |a 1 online resource 
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520 |a Vaccine discovery, financing, and distribution offer technical challenges requiring difficult choices. Patients, parents, providers, and politicians all must decide about who, when, where to vaccinate. Billions if not trillions of dollars and millions of lives depend on getting these choices right. Economics, the science of choice under uncertainty, can help clarify the principles for these choices. Yet standard economics models do not apply to most vaccines because they are a commodity offering both private benefit and risk as well as population level benefits through herd immunity. The book explains the vaccine development and financing landscape and the principles that invalidate standard market-based approaches to vaccine discovery and distribution based on free unregulated markets. Because government involvement in vaccine policy is universal, tools to determine costs and benefits of vaccination from various perspectives are explained and illustrated with exercises. The applications of economic evaluation to vaccines are presented with a range of sophistication from simple static models to advanced stochastic Markov models with dynamic effects of secondary disease transmission. Finally the book covers the need to plan and provide for public and private financing for vaccine discovery, production, and distribution. Throughout the book there is a focus on showing the benefits as well as the limitations of an exclusive focus on economic efficiency. Applied exercises help readers immediately begin to apply principles to typical problems facing decision-makers. 
505 0 |a Cover -- Series -- Handbook of Applied Health Economics in Vaccines -- Copyright -- Contents -- Introduction to the handbook -- Acknowledgments -- List of abbreviations -- Contributors -- 1 Principles of vaccine economics -- 1.0 Section introduction: principles of vaccine economics -- 1.1 Introduction to global vaccine systems -- 1.2 Relevance of health economics to vaccines -- 1.3 Cost of finding and making vaccines: implications for immunization programs -- 1.4 Vaccination as investment in human capital -- 1.5 Economics of vaccine delivery -- 2 Estimating the cost of immunization services 
505 8 |a 2.0 Section introduction: estimating the cost of immunization services -- 2.1 Why costing studies are needed -- 2.2 Defining immunization costs -- 2.3 Designing a primary costing study or analysis -- 2.4 Data analysis -- 2.5 Costing new vaccine introduction -- 3 Economic evaluation of vaccines and vaccine programs -- 3.0 Section introduction: economic evaluation of vaccines and vaccine programs -- 3.1 Overview of decision analysis and cost-​effectiveness -- 3.2 Defining the scope and study design of cost-​effectiveness analysis -- 3.3 Parameter estimation 
505 8 |a 3.4 Measuring and valuing health outcomes -- 3.5 Reporting and interpreting results of economic evaluation -- 3.6 Budget impact analysis and return on investment -- 3.7 Introduction to decision tree modeling -- 4 Advanced methods in economic evaluation -- 4.0 Section introduction: advanced methods in economic evaluation -- 4.1 Introduction to Markov modeling -- 4.2 Static and dynamic modeling -- 4.3 Probabilistic sensitivity analysis and value of information analysis -- 4.4 Economic evaluation reference case with Markov model -- 5 Financing and resource tracking of vaccination programs 
505 8 |a 5.0 Section introduction: financing and resource tracking of vaccination programs -- 5.1 Introduction to immunization financing and expenditure -- 5.2 Financing of immunization programs -- 5.3 Donor architecture for immunization financing -- Appendix 1. Exercise: a case study on estimating the total and unit routine immunization costs from the facility to the national level -- Appendix 2. Exercise: estimating new vaccine introduction costs -- Appendix 3. Immunization activities and line item costs -- Appendix 4. Markov decision processes 
505 8 |a Appendix 5. Derivation of the annual expected costs associated with the Infected state -- Appendix 6. Making models probabilistic and estimating the value of information -- Appendix 7. Decision model -- Index 
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650 0 |a Medical economics. 
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650 6 |a Économie de la santé. 
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650 7 |a Vaccines  |x Economic aspects  |2 fast 
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700 1 |a Brenzel, Logan E.,  |e editor. 
700 1 |a Padula, William,  |e editor. 
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