Computational and Analytic Methods in Biological Sciences : Bioinformatics with Machine Learning and Mathematical Modelling /

Bibliographic Details
Corporate Author: Taylor & Francis
Other Authors: Makrariya, Akshara (Editor)
Format: eBook
Language:English
Published: Gistrup, Denmark : River Publishers, [2023]
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Cover
  • Half Title
  • Series Page
  • Title Page
  • Copyright Page
  • Table of Contents
  • Preface
  • List of Figures
  • List of Tables
  • List of Contributors
  • List of Abbreviations
  • Chapter 1: Modeling of Smoking Transmission Dynamics using Caputo-Fabrizio Type Fractional Derivative
  • 1.1: Introduction
  • 1.2: Basic Concept of Fractional Operators
  • 1.3: Model Formulation
  • 1.4: Caputo-Fabrizio Fractional Order Derivative
  • 1.4.1: Stability Analysis of Model by Using Fixed-Point Theory
  • 1.5: Numerical Results and Discussion
  • 1.6: Conclusion
  • References
  • Chapter 2: Hybrid Feature Selection Techniques Utilizing Soft Computing Methods for Classifying Microarray Cancer Data
  • 2.1: Introduction
  • 2.2: Proposed Framework
  • 2.2.1: Genes Extraction by ICA
  • 2.2.2: Genetic Bee Colony (GBC) Algorithm
  • 2.3: Used Classifier
  • 2.3.1: Naive Bayes Classifier (NBC)
  • 2.3.2: Support Vector Machine (SVM) Classifier
  • 2.4: Experimental Setups
  • 2.5: Experimental Result
  • 2.6: Conclusion
  • References
  • Chapter 3: Finite Element Technique to Explicate Calcium Diffusion in Alzheimer's Disease
  • 3.1: Introduction
  • 3.2: Literature Survey
  • 3.3: Mathematical Formulations
  • 3.3.1: Calcium Buffering
  • 3.3.2: Voltage Gated Calcium Channel (VGCC)
  • 3.3.3: Endoplasmic Reticulum (ER)
  • 3.4: The Finite Element Technique
  • 3.4.1: Approximated Geometry of the Cell
  • 3.4.2: Physiological Boundary Conditions
  • 3.4.3: Meshing of the domain
  • 3.5: Results and Discussion
  • 3.5.1: For Hippocampal Neuron
  • 3.5.2: For Basal Forebrain Neuron
  • 3.6: Conclusion
  • References
  • Chapter 4: Comparative Analysis of Computational Methods used in Protein-Protein Interaction (PPI) Studies
  • 4.1: Introduction
  • 4.1.1: Protein
  • 4.1.2: Protein-Protein Interaction
  • 4.1.2.1: Protein-protein interfacial characteristics
  • 4.1.2.1.1: Size and shape.
  • 4.1.2.1.2: Complementarity between surfaces
  • 4.1.2.1.3: Residue interface propensities
  • 4.1.2.1.4: Hydrophobicity including Hydrogen bonding
  • 4.1.2.1.5: Segmentation and secondary structure
  • 4.1.2.1.6: Conformational changes on complex formation
  • 4.1.2.2: PPI types
  • 4.1.2.2.1: Homo oligomeric and Hetero oligomeric
  • 4.1.2.2.2: Obligate and non obligate complexes
  • 4.1.2.2.3: Transient and permanent complexes
  • 4.1.2.2.4: Disordered to ordered complexes
  • 4.1.2.3: PPI methods classification
  • 4.2: In Silico Methods
  • 4.2.1: Sequence Based Approaches
  • 4.2.1.1: Ortholog based sequence approach
  • 4.2.1.2: Domain pairs-based sequence approach
  • 4.2.1.3: Statistical sequence-based approaches
  • 4.2.1.3.1: Mirror tree method
  • 4.2.1.3.2: PIPE
  • 4.2.1.3.3: Co-evolutionary divergence
  • 4.2.1.4: Machine learning sequence-based approaches
  • 4.2.1.4.1: Auto-covariance
  • 4.2.1.4.2: Pairwise similarity
  • 4.2.1.4.3: Amino acid composition
  • 4.2.1.4.4: Amino acid triad
  • 4.2.1.4.5: UNISPPI
  • 4.2.1.4.6: ETB viterbi
  • 4.2.2: Structure Based Approaches
  • 4.2.2.1: Template structure-based approaches
  • 4.2.2.1.1: PRISM
  • 4.2.2.1.2: PREPPI
  • 4.2.2.2: Statistical structure-based approach
  • 4.2.2.2.1: PID matrix score
  • 4.2.2.2.2: Pre SPI
  • 4.2.2.2.3: Domain cohesion and coupling
  • 4.2.2.2.4: MEGADOCK
  • 4.2.2.2.5: MetaApproach
  • 4.2.2.3: Machine learning structure-based approaches
  • 4.2.2.3.1: Random forest
  • 4.2.2.3.2: Struct2Net
  • 4.2.3: Gene Neighbourhood
  • 4.2.4: Gene Fusion
  • 4.2.5: In Silico Two-hybrid (I2h)
  • 4.2.6: Phylogenetic Tree
  • 4.2.7: Phylogenetic Profile
  • 4.2.8: Gene Expression
  • 4.3: PPI Networks and Databases
  • 4.3.1: Creation of the PPI Networks
  • 4.3.1.1: Choice of databases and data selection
  • 4.3.1.2: Visualising PPI network
  • 4.3.2: Different Databases
  • 4.3.2.1: Interaction database.
  • 4.3.2.2: Metamining databases
  • 4.3.2.3: Predictive interaction databases
  • 4.3.2.4: Pathway database
  • 4.3.2.5: Unifying database
  • 4.4: Softwares Available for PPI
  • 4.5: Conclusion
  • References
  • Chapter 5: Optimization of COVID-19 Risk Factors Using Fuzzy Logic Inference System
  • 5.1: Introduction
  • 5.2: Methodology
  • 5.2.1: Proposed Mamdani Fuzzy Control System
  • 5.2.2: Fuzzy Controller Design
  • 5.2.3: Parameters Identification
  • 5.2.4: Fuzzification
  • 5.2.5: Fuzzy Inference Rule Base
  • 5.2.6: Rule Evaluation By Fuzzy Inference Engine
  • 5.2.7: Defuzzification
  • 5.3: Results
  • 5.4: Discussion
  • 5.5: Conclusion and Future Work
  • References
  • Chapter 6: Dynamical Analysis of the Fractional-Order Mathematical Model of Hashimoto's Thyroiditis
  • 6.1: Introduction
  • 6.2: Preliminaries
  • 6.3: Formulation of Fractional-Order Model of Hashimoto's Thyroiditis
  • 6.4: Stability Analysis
  • 6.5: Construction of a Numerical Solution Scheme
  • 6.6: Numerical Segment
  • 6.7: Conclusions
  • References
  • Chapter 7: Heated Laminar Vertical Jet of Pseudoplastic Fluids-Against Gravity
  • 7.1: Introduction
  • 7.2: Basic Equations
  • 7.3: Results and Discussions
  • 7.4: Graphical Presentation
  • 7.5: Conclusion
  • References
  • Chapter 8: Analytical Solutions For Hydromagnetic Flow of Chemically Reacting Williamson Fluid Over a Vertical Cone and Wedge with Heat Source/Sink
  • 8.1: Introduction
  • 8.2: Formulation of the Problem
  • 8.3: Solution of the Problem
  • 8.4: Results and Discussion
  • 8.5: Conclusion
  • References
  • Chapter 9: Aboodh Transform Homotopy Perturbation Method for Solving Newell-Whitehead-Segel Equation
  • 9.1: Introduction
  • 9.2: Basic Definition of Aboodh Transform
  • 9.2.1: Some Properies of Aboodh Transform
  • 9.3: Idea of Aboodh Transform Homotopy Perturbation Method
  • 9.4: Some Illustrations
  • 9.5: Conclusion.
  • Chapter 13: Analysis of One-Dimensional Groundwater Recharge by Spreading using Hybrid Differential Transform and Finite Difference Method
  • 13.1: Introduction
  • 13.2: Research Gap
  • 13.3: Mathematical Formulation
  • 13.4: Methodology
  • 13.5: Hybrid Differential Transform and Finite Difference Method
  • 13.6: Solution
  • 13.7: Results and Discussion
  • 13.8: Conclusions
  • 13.9: Utilities of Research
  • References
  • Chapter 14: Numerical Solution of Physiological Thermoregulatory Disturbances in Cold Environment
  • 14.1: Introduction
  • 14.2: Material and Methods
  • 14.3: Result
  • 14.4: Discussion
  • References
  • Chapter 15: Mathematical Modelling of Transient Heat Conduction in Biological System by Finite Element Method and Coding in MATLAB
  • 15.1: Introduction
  • 15.2: General Procedure of Finite Element Method
  • 15.3: Process of Finite Element Method
  • 15.3.1: Definition of the Problem and its Domain: One Dimensional Thermal Equation of Biological System
  • 15.4: Steps Involved in Finite Element Process
  • 15.5: Model-2: One Dimensional Quadratic Interpolation Model
  • 15.5.1: Assumption of a Suitable form of Variation in T for Quadratic Element
  • 15.6: Assembly of Elements
  • 15.7: Matrix Form of Element Equation
  • 15.8: Algorithm and Computer Program to Solve Heat Equation using FEM in Matlab:
  • 15.9: Result and Discussion
  • References
  • Index
  • About the Editors.