Computational and Analytic Methods in Biological Sciences : Bioinformatics with Machine Learning and Mathematical Modelling /
| Corporate Author: | |
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| Other Authors: | |
| Format: | eBook |
| Language: | English |
| Published: |
Gistrup, Denmark :
River Publishers,
[2023]
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Cover
- Half Title
- Series Page
- Title Page
- Copyright Page
- Table of Contents
- Preface
- List of Figures
- List of Tables
- List of Contributors
- List of Abbreviations
- Chapter 1: Modeling of Smoking Transmission Dynamics using Caputo-Fabrizio Type Fractional Derivative
- 1.1: Introduction
- 1.2: Basic Concept of Fractional Operators
- 1.3: Model Formulation
- 1.4: Caputo-Fabrizio Fractional Order Derivative
- 1.4.1: Stability Analysis of Model by Using Fixed-Point Theory
- 1.5: Numerical Results and Discussion
- 1.6: Conclusion
- References
- Chapter 2: Hybrid Feature Selection Techniques Utilizing Soft Computing Methods for Classifying Microarray Cancer Data
- 2.1: Introduction
- 2.2: Proposed Framework
- 2.2.1: Genes Extraction by ICA
- 2.2.2: Genetic Bee Colony (GBC) Algorithm
- 2.3: Used Classifier
- 2.3.1: Naive Bayes Classifier (NBC)
- 2.3.2: Support Vector Machine (SVM) Classifier
- 2.4: Experimental Setups
- 2.5: Experimental Result
- 2.6: Conclusion
- References
- Chapter 3: Finite Element Technique to Explicate Calcium Diffusion in Alzheimer's Disease
- 3.1: Introduction
- 3.2: Literature Survey
- 3.3: Mathematical Formulations
- 3.3.1: Calcium Buffering
- 3.3.2: Voltage Gated Calcium Channel (VGCC)
- 3.3.3: Endoplasmic Reticulum (ER)
- 3.4: The Finite Element Technique
- 3.4.1: Approximated Geometry of the Cell
- 3.4.2: Physiological Boundary Conditions
- 3.4.3: Meshing of the domain
- 3.5: Results and Discussion
- 3.5.1: For Hippocampal Neuron
- 3.5.2: For Basal Forebrain Neuron
- 3.6: Conclusion
- References
- Chapter 4: Comparative Analysis of Computational Methods used in Protein-Protein Interaction (PPI) Studies
- 4.1: Introduction
- 4.1.1: Protein
- 4.1.2: Protein-Protein Interaction
- 4.1.2.1: Protein-protein interfacial characteristics
- 4.1.2.1.1: Size and shape.
- 4.1.2.1.2: Complementarity between surfaces
- 4.1.2.1.3: Residue interface propensities
- 4.1.2.1.4: Hydrophobicity including Hydrogen bonding
- 4.1.2.1.5: Segmentation and secondary structure
- 4.1.2.1.6: Conformational changes on complex formation
- 4.1.2.2: PPI types
- 4.1.2.2.1: Homo oligomeric and Hetero oligomeric
- 4.1.2.2.2: Obligate and non obligate complexes
- 4.1.2.2.3: Transient and permanent complexes
- 4.1.2.2.4: Disordered to ordered complexes
- 4.1.2.3: PPI methods classification
- 4.2: In Silico Methods
- 4.2.1: Sequence Based Approaches
- 4.2.1.1: Ortholog based sequence approach
- 4.2.1.2: Domain pairs-based sequence approach
- 4.2.1.3: Statistical sequence-based approaches
- 4.2.1.3.1: Mirror tree method
- 4.2.1.3.2: PIPE
- 4.2.1.3.3: Co-evolutionary divergence
- 4.2.1.4: Machine learning sequence-based approaches
- 4.2.1.4.1: Auto-covariance
- 4.2.1.4.2: Pairwise similarity
- 4.2.1.4.3: Amino acid composition
- 4.2.1.4.4: Amino acid triad
- 4.2.1.4.5: UNISPPI
- 4.2.1.4.6: ETB viterbi
- 4.2.2: Structure Based Approaches
- 4.2.2.1: Template structure-based approaches
- 4.2.2.1.1: PRISM
- 4.2.2.1.2: PREPPI
- 4.2.2.2: Statistical structure-based approach
- 4.2.2.2.1: PID matrix score
- 4.2.2.2.2: Pre SPI
- 4.2.2.2.3: Domain cohesion and coupling
- 4.2.2.2.4: MEGADOCK
- 4.2.2.2.5: MetaApproach
- 4.2.2.3: Machine learning structure-based approaches
- 4.2.2.3.1: Random forest
- 4.2.2.3.2: Struct2Net
- 4.2.3: Gene Neighbourhood
- 4.2.4: Gene Fusion
- 4.2.5: In Silico Two-hybrid (I2h)
- 4.2.6: Phylogenetic Tree
- 4.2.7: Phylogenetic Profile
- 4.2.8: Gene Expression
- 4.3: PPI Networks and Databases
- 4.3.1: Creation of the PPI Networks
- 4.3.1.1: Choice of databases and data selection
- 4.3.1.2: Visualising PPI network
- 4.3.2: Different Databases
- 4.3.2.1: Interaction database.
- 4.3.2.2: Metamining databases
- 4.3.2.3: Predictive interaction databases
- 4.3.2.4: Pathway database
- 4.3.2.5: Unifying database
- 4.4: Softwares Available for PPI
- 4.5: Conclusion
- References
- Chapter 5: Optimization of COVID-19 Risk Factors Using Fuzzy Logic Inference System
- 5.1: Introduction
- 5.2: Methodology
- 5.2.1: Proposed Mamdani Fuzzy Control System
- 5.2.2: Fuzzy Controller Design
- 5.2.3: Parameters Identification
- 5.2.4: Fuzzification
- 5.2.5: Fuzzy Inference Rule Base
- 5.2.6: Rule Evaluation By Fuzzy Inference Engine
- 5.2.7: Defuzzification
- 5.3: Results
- 5.4: Discussion
- 5.5: Conclusion and Future Work
- References
- Chapter 6: Dynamical Analysis of the Fractional-Order Mathematical Model of Hashimoto's Thyroiditis
- 6.1: Introduction
- 6.2: Preliminaries
- 6.3: Formulation of Fractional-Order Model of Hashimoto's Thyroiditis
- 6.4: Stability Analysis
- 6.5: Construction of a Numerical Solution Scheme
- 6.6: Numerical Segment
- 6.7: Conclusions
- References
- Chapter 7: Heated Laminar Vertical Jet of Pseudoplastic Fluids-Against Gravity
- 7.1: Introduction
- 7.2: Basic Equations
- 7.3: Results and Discussions
- 7.4: Graphical Presentation
- 7.5: Conclusion
- References
- Chapter 8: Analytical Solutions For Hydromagnetic Flow of Chemically Reacting Williamson Fluid Over a Vertical Cone and Wedge with Heat Source/Sink
- 8.1: Introduction
- 8.2: Formulation of the Problem
- 8.3: Solution of the Problem
- 8.4: Results and Discussion
- 8.5: Conclusion
- References
- Chapter 9: Aboodh Transform Homotopy Perturbation Method for Solving Newell-Whitehead-Segel Equation
- 9.1: Introduction
- 9.2: Basic Definition of Aboodh Transform
- 9.2.1: Some Properies of Aboodh Transform
- 9.3: Idea of Aboodh Transform Homotopy Perturbation Method
- 9.4: Some Illustrations
- 9.5: Conclusion.
- Chapter 13: Analysis of One-Dimensional Groundwater Recharge by Spreading using Hybrid Differential Transform and Finite Difference Method
- 13.1: Introduction
- 13.2: Research Gap
- 13.3: Mathematical Formulation
- 13.4: Methodology
- 13.5: Hybrid Differential Transform and Finite Difference Method
- 13.6: Solution
- 13.7: Results and Discussion
- 13.8: Conclusions
- 13.9: Utilities of Research
- References
- Chapter 14: Numerical Solution of Physiological Thermoregulatory Disturbances in Cold Environment
- 14.1: Introduction
- 14.2: Material and Methods
- 14.3: Result
- 14.4: Discussion
- References
- Chapter 15: Mathematical Modelling of Transient Heat Conduction in Biological System by Finite Element Method and Coding in MATLAB
- 15.1: Introduction
- 15.2: General Procedure of Finite Element Method
- 15.3: Process of Finite Element Method
- 15.3.1: Definition of the Problem and its Domain: One Dimensional Thermal Equation of Biological System
- 15.4: Steps Involved in Finite Element Process
- 15.5: Model-2: One Dimensional Quadratic Interpolation Model
- 15.5.1: Assumption of a Suitable form of Variation in T for Quadratic Element
- 15.6: Assembly of Elements
- 15.7: Matrix Form of Element Equation
- 15.8: Algorithm and Computer Program to Solve Heat Equation using FEM in Matlab:
- 15.9: Result and Discussion
- References
- Index
- About the Editors.