Molecular Medicine : How Science Works /

The fascinating area of molecular medicine provides a molecular and cellular description of health and disease. Starting with the understanding of gene regulation and epigenetics, id est, the interplay of transcription factors and chromatin, this book will provide an fundamental basis of nearly all...

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Bibliographic Details
Main Authors:	Carlberg, Carsten (Author), Velleuer, Eunike (Author), Molnár, Ferdinand (Author)
Corporate Author:	SpringerLink (Online service)
Format:	eBook
Language:	English
Published:	Cham : Springer International Publishing : Imprint: Springer, 2023.
Edition:	1st ed. 2023.
Subjects:	Medicine > Research. Biology > Research. Genomics. Cancer. Immunology. Nutrition . Physiology. Biomedical Research. Cancers. Nutrition. Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

1. The human genome and its variations
2. Gene expression and chromatin
3. The basal transcriptional machinery
4. Transcription factors and signal transduction
5. A key transcription factor family: Nuclear receptors
6. DNA methylation
7. Histone modifications
8. Chromatin remodeling and organization
9. Regulatory impact of non-coding RNA
10. Genome-wide principles of gene regulation
11. Epigenetics in development
12. Epigenetics and aging
13. Epigenetics and disease
14. Cells and tissues of the immune system
15. Innate immunity and inflammation
16. Adaptive immunity and antigen receptor diversity
17. B cell immunity: BCRs, antibodies and their effector functions
18. Antigen-presenting cells and MHCs
19. T cell immunity: TCRs and their effector functions
20. Immunity to bacterial pathogens and the microbiome
21. Immunity to viral pathogens and the virome
22. Tolerance and transplantation immunology
23. Immunological hypersensitivities: Allergy and autoimmunity
24. Introduction to cancer
25. Oncogenes, signal transduction and the hallmarks of cancer
26 Tumor suppressor genes and cell fate control
27. Multistep tumorigenesis and genome instability
28. Cancer genomics
29. Cancer epigenomics.-30. Aging and cancer
31. Tumor microenvironment
32 Metastasis and cachexia
33. Cancer immunology
34 Architecture of cancer therapies
35 Nutrition and common diseases
36 Interference of the human genome with nutrients
37. Nutritional epigenetics, signaling and aging
38. Chronic inflammation and metabolic stress
39. Obesity
40. Insulin resistance and diabetes
41. Heart disease and the metabolic syndrome
42 Epigenetics, inflammation and disease.