Bacterial toxins : tools in cell biology and pharmacology /

This is a survey of well characterized and recently discovered bacterial protein toxins. Leading investigators of the respective toxins review the various molecular mechanisms of action, ranging from toxin-induced ADP-ribosylation up to membrane perforation by pore-forming toxins. Thy also describe...

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Bibliographic Details
Other Authors: Aktories, K.
Format: eBook
Language:English
Published: London ; New York : Chapman & Hall, ©1997.
Series:Laboratory companion.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Ch. 1. Cholera Toxin: Mechanism of Action and Potential Use in Vaccine Development / G.-F. Zhang, W.A. Patton and J. Moss
  • Ch. 2. Cholera Toxin and Escherichia coli Heat-labile Enterotoxin: Biochemical Methods for Assessing Enzymatic Activities / W.A. Patton, G.-F. Zhang and J. Moss
  • Ch. 3. Pertussis Toxin / C. Locht and R. Antoine
  • Ch. 4. Pertussis Toxin as a Cell Biology Tool / B. Nurnberg
  • Ch. 5. Clostridium botulinum ADP-ribosyltransferase C3 / K. Aktories and G. Koch
  • Ch. 6. Clostridium botulinum C3 Exoenzyme and Studies on Rho Proteins / C.D. Nobes and A. Hall
  • Ch. 7. Preparation of Clostridium botulinum C3 Exoenzyme and Application of ADP-ribosylation of Rho Proteins in Biological Systems / Y. Saito and S. Narumiya
  • Ch. 8. Actin-ADP-ribosylating Toxins: Cytotoxic Mechanisms of Clostridium botulinum C2 Toxin and Clostridium perfringens Iota Toxin / K. Aktories, P. Sehr and I. Just
  • Ch. 9. Purification, Activation and Endocytosis of Botulinum C2 Toxin / I. Ohishi
  • Ch. 10. The Role of the Clostridium botulinum C2 Toxin as a Research Tool to Study Eucaryotic Cell Biology / I.L. Simpson
  • Ch. 11. Probing the Actin Cytoskeleton by Clostridium botulinum C2 Toxin and Clostridium perfringes Iota Toxin / K. Aktories, U. Prepens and P. Sehr
  • Ch. 12. Clostridium difficile Toxins / M. Thelestam, I. Florin and E. Chaves-Olarte
  • Ch. 13. Clostridium difficile Toxin B as a Probe for Rho GTPases / I. Just, J. Selzer and F. Hofmann
  • Ch. 14. Clostridial Neurotoxins / G. Schiavo and C. Montecucco
  • Ch. 15. Isolated Nerve Terminals as a Model System for the Study of Botulinum and Tetanus Toxins / J. Blasi, E. Link and R. Jahn
  • Ch. 16. Clostridial Toxins and Endocrine Secretion: Their Use in Insulin-Secreting Cells / J. Lang, R. Regazzi and C.B. Wollheim
  • Ch. 17. Pore-forming Toxins / S. Bhakdi, A. Valeva and I. Walev
  • Ch. 18. Application of Alpha-toxin and Streptolysin O as Tools in Cell Biological / G. Ahnert-Hilger and U. Weller
  • Ch. 19. Toxins as Transporting Tools / S. Olsnes, O. Klingenberg and R. Munoz
  • Ch. 20. A Brief Guide to the Safe Handling of Biological Toxin / A.B. Maksymowych and L.L. Simpson.