Structure-based ligand design /
Most drugs bind to a clearly defined macromolecular target that is complementary in terms of structure and chemistry. This observation is the basic paradigm of structure-based ligand design. Although this method first emerged in the 1980s, it has already become a powerful tool for pharmaceutical res...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Weinheim ; New York :
Wiley-VCH,
©1998.
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| Series: | Methods and principles in medicinal chemistry ;
v. 6. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | Most drugs bind to a clearly defined macromolecular target that is complementary in terms of structure and chemistry. This observation is the basic paradigm of structure-based ligand design. Although this method first emerged in the 1980s, it has already become a powerful tool for pharmaceutical research. Much has been learned, however, since the first attempts to discover drugs on the basis of available biochemical and structural data. Nowadays, structure-based ligand design is an established method for creating drugs with new structural features, for modifying binding activities and pharmaco. |
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| Physical Description: | 1 online resource (xiv, 153 pages) : illustrations |
| Format: | Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9783527612161 3527612165 9783527612178 3527612173 |