rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Chemogenomics in drug discovery
    sub title: a medicinal chemistry perspective
  name:
    name part: Kubinyi, Hugo.
  name:
    name part: Müller, Gerhard
    name part: 1963-
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: gw
    place:
      place term: Weinheim
    publisher: Wiley-VCH
    date issued: ©2004
    date issued: 2004
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xxiv, 463 pages) : illustrations (some color), portrait
  abstract: Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics. The first reference devoted to the topic, this up-to-date resource covers all stages of the early drug discovery process, from target selection to compound library and lead design. With the combined expertise of 20 research groups from academia and from leading pharmaceutical companies, this book is a must-have for every drug developer and medicinal chemist applying the powerful methods of chemogenomics to speed up the drug discovery process.
  table of contents: Target family-directed masterkeyes in chemogenomics / Gehard Müller -- Drug discovery from side effects / Hugo Kubinyi -- The value of chemical genetics in drug discovery / Keith Russell and William F. Michne -- Structural aspects of binding site similarity: a 3D upgrade for chemogenomics / Andreas Bergner and Judith Günther -- The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds / Edgar Jacoby, Ansgar Schuffenhauer, and Pierre Acklin -- Chemical kinomics / Bert M. Klebl, Henrik Daub, and György Kéri -- Structural aspects of kinases and their inhibitors / Rogier Buijsman -- A chemical genomics approach for ion channel modulators / Karl-Heinz Baringhaus and Gerhard Hessler -- Phosphodiesterase inhibitors: a chemogenomic view / Martin Hendrix and Christopher Kallus -- Proteochemometrics: a tool for modeling the molecular interaction space / Jarl E.S. Wikberg, Maris Lapinsch, and Peteris Prusis -- Some principles related to chemogenomics in compound library and template design for GPCRs / Thomas R. Webb -- Computational filters in lead generation: targeting drug-like chemotypes / Wolfgang Guba and Olivier Roche -- Navigation in chemical space: ligand-based design of focused compound libraries / Gisbert Schneider and Petra Schneider -- Natural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates / Marcus A. Koch and Herbert Waldmann -- Combinatorial chemistry in the age of chemical genomics / Reni Joseph and Prabhat Arya.
  note: edited by Hugo Kubinyi and Gerhard Müller.
  note: Includes bibliographical references and index.
  subject:
    topic: Drug development
  subject:
    topic: Pharmaceutical chemistry
  subject:
    topic: Pharmacogenetics
  subject:
    topic: Drugs
    topic: Design
  subject:
    topic: Genomics
  subject:
    topic: Drugs
    topic: Research
  subject:
    topic: Pharmacogenetics
  subject:
    topic: Drug Discovery
    topic: methods
  subject:
    topic: Combinatorial Chemistry Techniques
  subject:
    topic: Drug Design
  subject:
    topic: Genomics
  subject:
    topic: Chemistry, Pharmaceutical
  classification: RM301.25 .C495 2004eb
  classification: 615/.19
  classification: W1 ME9613H v.22 2004
  classification: QV 38 C517 2004
  related item:
    title info:
      title: Chemogenomics in drug discovery
    origin info:
      publisher: Weinheim : Wiley-VCH, ©2004
  related item:
    title info:
      title: Methods and principles in medicinal chemistry ; v. 22
  identifier: 3527604022
  identifier: 9783527604029
  identifier: 3527603948
  identifier: 9783527603947
  identifier: 352730987X
  identifier: 9783527309870
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: NhCcYBP
    record creation date: 060510
    record change date: 20260214211004.5
    record identifier: in00004689456
    language of cataloging:
      language term: eng