Protein-ligand interactions from molecular recognition to drug design /
The lock-and-key principle formulated by Emil Fischer as early as the end of the 19th century has still not lost any of its significance for the life sciences. The basic aspects of ligand-protein interaction may be summarized under the term 'molecular recognition' and concern the specifici...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Language Notes: | English. |
| Published: |
Weinheim :
Wiley-VCH,
©2003.
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| Series: | Methods and principles in medicinal chemistry ;
v. 19. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | The lock-and-key principle formulated by Emil Fischer as early as the end of the 19th century has still not lost any of its significance for the life sciences. The basic aspects of ligand-protein interaction may be summarized under the term 'molecular recognition' and concern the specificity as well as stability of ligand binding. Molecular recognition is thus a central topic in the development of active substances, since stability and specificity determine whether a substance can be used as a drug. Nowadays, computer-aided prediction and intelligent molecular design make a large contribution. |
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| Physical Description: | 1 online resource (xx, 242 pages) : illustrations |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 3527605517 9783527605514 3527601813 9783527601813 |