Protein crystallography in drug discovery /
The rational, structure-based approach has become standard in present-day drug design. As a consequence, the availability of high-resolution structures of target proteins is more often than not the basis for an entire drug development program. Protein structures suited for rational drug design are a...
| Other Authors: | , |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Weinheim :
Wiley-VCH,
©2004.
|
| Series: | Methods and principles in medicinal chemistry ;
v. 20. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | The rational, structure-based approach has become standard in present-day drug design. As a consequence, the availability of high-resolution structures of target proteins is more often than not the basis for an entire drug development program. Protein structures suited for rational drug design are almost exclusively derived from crystallographic studies, and drug developers are relying heavily on the power of this method. Here, researchers from leading pharmaceutical companies present valuable first-hand information, much of it published for the first time. They discuss strategies to derive hi. |
|---|---|
| Physical Description: | 1 online resource (xvi, 262 pages) : illustrations. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9783527606351 3527606351 3527601872 9783527601875 |