Chemical engineering in the pharmaceutical industry : drug product design, development and modeling /
A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design an...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Hoboken, NJ, USA :
Wiley/AIChe,
2019.
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| Edition: | Second edition. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Preface; Contributors; Unit Conversions and Commonly used Formulas; Part I Introduction; Chapter 1 Chemical Engineering in the Pharmaceutical Industry: An Introduction; Part II Drug Product Design, Development & Modeling; Chapter 2 Design of Solid Dosage Formulations; Chapter 3 Powder Process Challenges and Solutions; Chapter 4 Design and Scale-up of Dry Granulation Processes; Chapter 5 Model based development of roller compaction processes; Chapter 6 Wet Granulation Processes; Chapter 7 Towards a generic model for twin-screw wet granulation; Chapter 8 Modeling a dosator capsule filling process for hard-shell capsules; Chapter 9 Powder Compaction
- Process Design and Understanding; Chapter 10 Punch Sticking: Factors and Solutions; Chapter 11 Spray Atomization Modeling for Tablet Film Coating Processes; Chapter 12 Spray Drying and Amorphous Dispersions; Chapter 13 The Freeze Drying Process: The Use of Mathematical Modeling in Process Design, Understanding and Scale-up; Chapter 14 Sterilization Processes in the Pharmaceutical Industry; Chapter 15 Controlled Release Technology and Design of Oral Controlled Release Dosage Forms; Chapter 16 Process Design and Development for Novel Pharmaceutical Dosage Forms; Chapter 17 Multiscale Modeling of a Pharmaceutical Fluid-bed Coating Process: Using CFD/DEM and Population-balance Models to Predict Coating Uniformity; Chapter 18 Process Design of Topical Semi-solids: Application of Fundamental Concepts in Pharmaceutical Engineering to PEG Ointment Development; Chapter 19 Achieving a Hot Melt Extrusion Design Space for the Production of Solid Solutions; Chapter 20 Drug Product Process Modeling; Part III Continuous Manufacturing; Chapter 21 Continuous Manufacturing in Secondary Production; Chapter 22 Continuous Direct Compression Using Portable Continuous Miniature Modular & Manufacturing (PCM & M); Chapter 23 Process control levels for continuous pharmaceutical tablet manufacturing; Part IV Applied Statistics / Regulatory Environment; Chapter 24 Multivariate Analysis for Pharmaceutical and Medical Device Development; Chapter 25 Pharmaceutical Manufacturing: The Role of Multivariate Analysis in Design Space, Control Strategy, Process Understanding, Troubleshooting, and Optimization; Chapter 26 Quality by Design: Pilot to Reality
- The Honeymoon Phase to the Stormy Years