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Quantitative pharmacology and individualized therapy strategies in development of therapeutic proteins for immune-mediated inflammatory diseases /

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"Focused on quantitative pharmacology and individualized therapy for developing biotherapeutics in immune-mediated inflammatory diseases, this book discusses both theoretical and practical aspects and includes case studies illustrating applications in drug development. Provides frontline knowle...

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Bibliographic Details
Other Authors: Zhou, Honghui (Editor), Mould, Diane R. (Diane Renee), 1960- (Editor)
Format: eBook
Language:English
Published: Hoboken, NJ : Wiley, 2019.
Subjects:
Immunologic diseases > Treatment.
Pharmacology.
Mathematical models.
Autoimmune Diseases > drug therapy
Proteins > therapeutic use
Proteins > pharmacokinetics
Protein Engineering > methods
Models, Theoretical
Pharmacology
Online Access:Connect to the full text of this electronic book
Description
Summary:"Focused on quantitative pharmacology and individualized therapy for developing biotherapeutics in immune-mediated inflammatory diseases, this book discusses both theoretical and practical aspects and includes case studies illustrating applications in drug development. Provides frontline knowledge of using PK/PD modeling tools to address a variety of problems in development of therapeutic proteins. Reviews and discusses biomarkers, systems pharmacology, PBPK modeling, and target-mediated modeling, as translational tools. Helps readers understand disease progression and identify of mechanisms-based biomarkers with clinical relevance"--Provided by publisher.
Item Description:"John Wiley & Sons Inc."--tp verso.
Physical Description:1 online resource
Bibliography:Includes bibliographical references and index.
ISBN:9781119289210
1119289211
9781119289227
111928922X
9781119289234
1119289238